Department Brüning

Journal Article (185)

2018
Journal Article
Jiang, H.; Brüning, J. C.: Melanin-concentrating hormone-dependent control of feeding: when volume matters. Cell Metabolism 28 (1), pp. 7 - 8 (2018)
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Korotkova, T.; Ponomarenko, A.; Monaghan, C. K.; Poulter, S. L.; Cacucci, F.; Wills, T.; Hasselmo, M. E.; Lever, C.: Reconciling the different faces of hippocampal theta: The role of theta oscillations in cognitive, emotional and innate behaviors. Neuroscience and Biobehavioral Reviews 85, pp. 65 - 80 (2018)
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Löhr, H.; Hess, S.; Robalo de Azevedo Aleixo Pereira, M. M.; Reinoß, P.; Leibold, S.; Schenkel, C.; Wunderlich, C. M.; Kloppenburg, P.; Brüning, J. C.; Hammerschmidt, M.: Diet-induced growth is regulated via acquired Leptin resistance and engages a Pomc-somatostatin-growth hormone circuit. Cell Reports 23 (6), pp. 1728 - 1741 (2018)
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Mittenbühler, M.; Sprenger, H.-G.; Gruber, S.; Wunderlich, C. M.; Kern, L.; Brüning, J. C.; Wunderlich, F. T.: Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma. Molecular Metabolism 17, pp. 122 - 133 (2018)
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Ponomarenko, A.; Korotkova, T.: Hunger is a gatekeeper of pain in the brain. Nature 556 (7702), pp. 445 - 446 (2018)
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Quinones, M.; Al-Massadi, O.; Folgueira, C.; Bremser, S.; Gallego, R.; Torres-Leal, L.; Haddad-Tovolli, R.; Carcia-Caceres, C.; Hernandez-Bautista, R.; Lam, B. Y.H. et al.; Beiroa, D.; Sanchez-Rebordelo, E.; Senra, A.; Malagon, J. A.; Valeria, P.; Fondevila, M. F.; Ferno, J.; Malagon, M. M.; Contreras, R.; Pfluger, P.; Brüning, J. C.; Yeo, G.; Tschöp, M. H.; Dieguez, C.; Lopez, M.; Claret, M.; Kloppenburg, P.; Sabio, G.; Nogueiras, R.: p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1. Nature Communications 9 (1), 3432 (2018)
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Schmidt, E.; Dhaouadi, I.; Gaziano, I.; Oliverio, M.; Klemm, P.; Awazawa, M.; Mitterer, G.; Fernandez-Rebollo, E.; Pradas-Juni, M.; Wagner, W. et al.; Hammerschmidt, P.; Loureiro, R.; Kiefer, C.; Hansmeier, N. R.; Frommolt, P.; Zentis, P.; Orom, U. A.; Heeren, J.; Blüher, M.; Bilban, M.; Kornfeld, J.-W.: LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat. Nature Communications 9, 3622 (2018)
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Schüler, R.; Seebeck, N.; Osterhoff, M. A.; Witte, V.; Flöel, A.; Busjahn, A.; Jais, A.; Brüning, J. C.; Frahnow, T.; Kabisch, S. et al.; Pivovarova, O.; Hornemann, S.; Kruse, M.; Pfeiffer, A. F.H.: VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humans. Molecular Metabolism 11 (May), pp. 129 - 136 (2018)
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Timper, K.; Paeger, L.; Sanchez-Lasheras, C.; Varela, L.; Jais, A.; Nolte, H.; Vogt, M. C.; Hausen, A. C.; Heilinger, C.; Evers, N. et al.; Pospisilik, J. A.; Penninger, J. M.; Taylor, E. B.; Horvath, T. L.; Kloppenburg, P.; Brüning, J. C.: Mild impairment of mitochondrial OXPHOS promotes fatty acid utilization in POMC neurons and improves glucose homeostasis in obesity. Cell Reports 25 (2), pp. 383 - 397 (2018)
Journal Article
Wunderlich, C. M.; Ackermann, J. P.; Ostermann, A. L.; Adams-Quack, P.; Vogt, M. C.; Tran, M.-L.; Nikolajev, A.; Waisman, A.; Garbers, C.; Theurich, S. et al.; Mauer, J.; Hövelmeyer, N.; Wunderlich, F. T.: Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nature Communications 9 (1), 1646 (2018)
Journal Article
Zhou, J.; Wan, J.; Shu, X. E.; Heß, M. E.; Brüning, J. C.; Qian, S.-B.: N6-Methyladenosine guides mRNA alternative translation during integrated stress response. Molecular Cell 69 (4), pp. 636 - 647.e7 (2018)
2017
Journal Article
Awazawa, M.; Gabel, P.; Tsaousidou, E.; Nolte, H.; Krüger, M.; Schmitz, J.; Ackermann, J. P.; Brandt, C.; Altmueller, J.; Motameny, S. et al.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Brüning, J. C.: A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nature Medicine 23 (12), pp. 1466 - 1473 (2017)
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Blum, C. A.; Winzeler, B.; Nigro, N.; Schuetz, P.; Biethahn, S.; Kahles, T.; Mueller, C.; Timper, K.; Haaf, K.; Tepperberg, J. et al.; Amort, M.; Huber, A.; Bingisser, R.; Sándor, P. S.; Nedeltchev, K.; Müller, B.; Katan, M.; Christ-Crain, M.: Copeptin for risk stratification in non-traumatic headache in the emergency setting: a prospective multicenter observational cohort study. The Journal of Headache and Pain 18 (1), 21 (2017)
Journal Article
Braune, J.; Weyer, U.; Hobusch, C.; Mauer, J.; Brüning, J. C.; Bechmann, I.; Gericke, M.: IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophages in obesity. The Journal of Immunology 198 (7), pp. 2927 - 2934 (2017)
Journal Article
Chakupurakal, G.; Garcia-Marquez, M. A.; Shimabukuro-Vornhagen, A.; Kluth, S.; Schlosser, H.; Theurich, S.; Scheid, C.; Hallek, M.; Holtick, U.; von Bergwelt-Baildon, M.: Regulatory B10 cells display an altered homoeostasis in acute graft-versus-host disease. European Journal of Haematology 98 (2), pp. 128 - 133 (2017)
Journal Article
Chatzinikolaou, G.; Apostolou, Z.; Aid-Pavlidis, T.; Ioannidou, A.; Karakasilioti, I.; Papadopoulos, G. L.; Aivaliotis, M.; Tsekrekou, M.; Strouboulis, J.; Kosteas, T. et al.; Garinis, G. A.: ERCC1-XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes. Nature Cell Biology 19 (5), pp. 421 - 432 (2017)
Journal Article
Diaconescu, A. O.; Mathys, C.; Weber, L. A.E.; Kasper, L.; Mauer, J.; Stephan, K. E.: Hierarchical prediction errors in midbrain and septum during social learning. Social Cognitive and Affective Neuroscience 12 (4), pp. 618 - 634 (2017)
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Dodd, G. T.; Andrews, Z. B.; Simonds, S. E.; Michael, N. J.; DeVeer, M.; Brüning, J. C.; Spanswick, D.; Cowley, M. A.; Tiganis, T.: A hypothalamic phosphatase switch coordinates energy expenditure with feeding. Cell Metabolism 26 (2), pp. 375 - 393 (2017)
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Fritsche, A.; Heni, M.; Gancheva, S.; Preißl, H.; Kullmann, S.; Lehnert, H.; Hallschmid, M.; Tschöp, M. H.; Brüning, J. C.; Roden, M. et al.; Häring, H.-U.: Das Gehirn als Schaltzentrale des Stoffwechsels. Diabetes Aktuell 15 (3), pp. 109 - 111 (2017)
Journal Article
Geoerger, B.; Bourdeaut, F.; DuBois, S. G.; Fischer, M.; Geller, J. I.; Gottardo, N. G.; Marabelle, A.; Pearson, A. D.J.; Modak, S.; Cash, T. et al.; Robinson, G. W.; Motta, M.; Matano, A.; Bhansali, S. G.; Dobson, J. R.; Parasuraman, S.; Chi, S. N.: A phase I study of the CDK4/6 inhibitor ribociclib (LEE011) in pediatric patients with malignant rhabdoid tumors, neuroblastoma, and other solid tumors. Clinical Cancer Research 23 (10), pp. 2433 - 2441 (2017)
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