Publications

Awazawa, M.; Gabel, P.; Tsaousidou, E.; Nolte, H.; Krüger, M.; Schmitz, J.; Ackermann, J. P.; Brandt, C.; Altmueller, J.; Motameny, S. et al.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Brüning, J. C.: A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nature Medicine 23 (12), pp. 1466 - 1473 (2017)

Blum, C. A.; Winzeler, B.; Nigro, N.; Schuetz, P.; Biethahn, S.; Kahles, T.; Mueller, C.; Timper, K.; Haaf, K.; Tepperberg, J. et al.; Amort, M.; Huber, A.; Bingisser, R.; Sándor, P. S.; Nedeltchev, K.; Müller, B.; Katan, M.; Christ-Crain, M.: Copeptin for risk stratification in non-traumatic headache in the emergency setting: a prospective multicenter observational cohort study. The Journal of Headache and Pain 18 (1), 21 (2017)

Braune, J.; Weyer, U.; Hobusch, C.; Mauer, J.; Brüning, J. C.; Bechmann, I.; Gericke, M.: IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophages in obesity. The Journal of Immunology 198 (7), pp. 2927 - 2934 (2017)

Chakupurakal, G.; Garcia-Marquez, M. A.; Shimabukuro-Vornhagen, A.; Kluth, S.; Schlosser, H.; Theurich, S.; Scheid, C.; Hallek, M.; Holtick, U.; von Bergwelt-Baildon, M.: Regulatory B10 cells display an altered homoeostasis in acute graft-versus-host disease. European Journal of Haematology 98 (2), pp. 128 - 133 (2017)

Chatzinikolaou, G.; Apostolou, Z.; Aid-Pavlidis, T.; Ioannidou, A.; Karakasilioti, I.; Papadopoulos, G. L.; Aivaliotis, M.; Tsekrekou, M.; Strouboulis, J.; Kosteas, T. et al.; Garinis, G. A.: ERCC1-XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes. Nature Cell Biology 19 (5), pp. 421 - 432 (2017)

Diaconescu, A. O.; Mathys, C.; Weber, L. A.E.; Kasper, L.; Mauer, J.; Stephan, K. E.: Hierarchical prediction errors in midbrain and septum during social learning. Social Cognitive and Affective Neuroscience 12 (4), pp. 618 - 634 (2017)

Dodd, G. T.; Andrews, Z. B.; Simonds, S. E.; Michael, N. J.; DeVeer, M.; Brüning, J. C.; Spanswick, D.; Cowley, M. A.; Tiganis, T.: A hypothalamic phosphatase switch coordinates energy expenditure with feeding. Cell Metabolism 26 (2), pp. 375 - 393 (2017)

Fritsche, A.; Heni, M.; Gancheva, S.; Preißl, H.; Kullmann, S.; Lehnert, H.; Hallschmid, M.; Tschöp, M. H.; Brüning, J. C.; Roden, M. et al.; Häring, H.-U.: Das Gehirn als Schaltzentrale des Stoffwechsels. Diabetes Aktuell 15 (3), pp. 109 - 111 (2017)

Geoerger, B.; Bourdeaut, F.; DuBois, S. G.; Fischer, M.; Geller, J. I.; Gottardo, N. G.; Marabelle, A.; Pearson, A. D.J.; Modak, S.; Cash, T. et al.; Robinson, G. W.; Motta, M.; Matano, A.; Bhansali, S. G.; Dobson, J. R.; Parasuraman, S.; Chi, S. N.: A phase I study of the CDK4/6 inhibitor ribociclib (LEE011) in pediatric patients with malignant rhabdoid tumors, neuroblastoma, and other solid tumors. Clinical Cancer Research 23 (10), pp. 2433 - 2441 (2017)

Jais, A.; Brüning, J. C.: Hypothalamic inflammation in obesity and metabolic disease. The Journal of Clinical Investigation 127 (1), pp. 24 - 32 (2017)

Layer, J. P.; Kronmüller, M. T.; Quast, T.; van den Boorn-Konijnenberg, D.; Effern, M.; Hinze, D.; Althoff, K.; Schramm, A.; Westermann, F.; Peifer, M. et al.; Hartmann, G.; Tüting, T.; Kolanus, W.; Fischer, M.; Schulte, J. H.; Hölzel, M.: Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression. Oncoimmunology 6 (3), e1320626 (2017)

Lechner, A.; Schlößer, H.; Rothschild, S. I.; Thelen, M.; Reuter, S.; Zentis, P.; Shimabukuro-Vornhagen, A.; Theurich, S.; Wennhold, K.; Garcia-Marquez, M. et al.; Tharun, L.; Quaas, A.; Schauss, A.; Isensee, J.; Hucho, T.; Huebbers, C.; von Bergwelt-Baildon, M.; Beutner, D.: Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma. Oncotarget 8 (27), pp. 44418 - 44433 (2017)

Lodrini, M.; Sprüssel, A.; Astrahantseff, K.; Tiburtius, D.; Konschak, R.; Lode, H. N.; Fischer, M.; Keilholz, U.; Eggert, A.; Deubzer, H. E.: Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma. Oncotarget 8 (49), pp. 85234 - 85251 (2017)

Loh, K.; Zhang, L.; Brandon, A.; Wang, Q.; Begg, D.; Qi, Y.; Fu, M.; Kulkarni, R.; Teo, J.; Baldock, P. et al.; Brüning, J. C.; Cooney, G.; Neely, G. G.; Herzog, H.: Insulin controls food intake and energy balance via NPY neurons. Molecular Metabolism 6 (6), pp. 574 - 584 (2017)

Paeger, L.; Karakasilioti, I.; Altmueller, J.; Frommole, P.; Brüning, J. C.; Kloppenburg, P.: Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin. eLife 6, e25770 (2017)

Paeger, L.; Pippow, A.; Hess, S.; Paehler, M.; Klein, A. C.; Husch, A.; Pouzat, C.; Brüning, J. C.; Kloppenburg, P.: Energy imbalance alters Ca2+ handling and excitability of POMC neurons. eLife 6, e25641 (2017)

Pereira, M.; Mahu, I.; Seixas, E.; Martinez-Sanchez, N.; Kubasova, N.; Pirzgalska, R. M.; Cohen, P.; Dietrich, M. O.; Lopez, M.; Bernardes, G. J. et al.; Domingos, A. I.: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages. Nature Communications 8, 14967 (2017)

Pir, G. J.; Choudhary, B.; Mandelkow, E.: Caenorhabditis elegans models of tauopathy. The FASEB Journal 31 (12), pp. 5137 - 5148 (2017)

Ponomarenko, A.; Korotkova, T.: To eat? To sleep? To run? Coordination of innate behaviors by lateral hypothalamus. Neuroforum 23 (2), pp. A45 - A55 (2017)

Rao, S.; Sigl, V.; Wimmer, R. A.; Novatchkova, M.; Jais, A.; Wagner, G.; Handschuh, S.; Uribesalgo, I.; Hagelkruys, A.; Kozieradzki, I. et al.; Tortola, L.; Nitsch, R.; Cronin, S. J.; Orthofer, M.; Branstetter, D.; Canon, J.; Rossi, J.; D'Arcangelo, M.; Botling, J.; Micke, P.; La Fleur, L.; Edlund, K.; Bergqvist, M.; Ekman, S.; Lendl, T.; Popper, H.; Takayanagi, H.; Kenner, L.; Hirsch, F. R.; Dougall, W.; Penninger, J.: RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer. Genes and Development 31 (20), pp. 2099 - 2112 (2017)