Department Brüning

Journal Article (185)

2019
Journal Article
Pir, G. J.; Choudhary, B.; Kaniyappan, S.; Chandupatla, R. R.; Mandelkow, E.; Mandelkow, E.-M.; Wang, Y.: Suppressing Tau aggregation and toxicity by an anti-aggregant Tau fragment. Molecular Neurobiology 56 (5), pp. 3751 - 3767 (2019)
Journal Article
Raichur, S.; Brunner, B.; Bielohuby, M.; Hansen, G.; Pfenninger, A.; Wang, B.; Brüning, J. C.; Larsen, P. J.; Tennagels, N.: The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach. Molecular Metabolism 21, pp. 36 - 50 (2019)
Journal Article
Rao, S.; Mondragón, L.; Pranjic, B.; Hanada, T.; Stoll, G.; Köcher, T.; Zhang, P.; Jais, A.; Lercher, A.; Bergthaler, A. et al.; Schramek, D.; Haigh, K.; Sica, V.; Leduc, M.; Modjtahedi, N.; Pai, T.-P.; Onji, M.; Uribesalgo, I.; Hanada, R.; Kozieradzki, I.; Koglgruber, R.; Cronin, S. J.; She, Z.; Quehenberger, F.; Popper, H.; Kenner, L.; Haigh, J. J.; Kepp, O.; Rak, M.; Cai, K.; Kroemer, G.; Penninger, J.: AIF-regulated oxidative phosphorylation supports lung cancer development. Cell Research 29 (7), pp. 579 - 591 (2019)
Journal Article
Ruud, J.; Alber, J.; Tokarska, A.; Engström Ruud, L.; Nolte, H.; Biglari, N.; Lippert, R. N.; Lautenschlager, Ä.; Cieslak, P. E.; Szumiec, L. et al.; Hess, M. E.; Brönneke, H. S.; Krüger, M.; Nissbrandt, H.; Korotkova, T.; Silberberg, G.; Rodriguez Parkitna, J.; Brüning, J. C.: The Fat mass and obesity-associated protein (FTO) regulates locomotor responses to novelty via D2R medium spiny neurons. Cell Reports 27 (11), pp. 3182 - 3198.e9 (2019)
Journal Article
Thanarajah, S. E.; Backes, H.; DiFeliceantonio, A.; Albus, K.; Cremer, A. L.; Hanssen, R.; Lippert, R. N.; Cornely, O. A.; Small, D. M.; Brüning, J. C. et al.; Tittgemeyer, M.: Food intake recruits orosensory and post-ingestive dopaminergic circuits to affect eating desire in humans. Cell Metabolism 29 (3), pp. 695 - 706.e4 (2019)
Journal Article
Thanarajah, S. E.; Hoffstall, V.; Rigoux, L.; Hanssen, R.; Brüning, J. C.; Tittgemeyer, M.: The role of insulin sensitivity and intranasally applied insulin on olfactory perception. Scientific Reports 9, 7222 (2019)
Journal Article
Turpin-Nolan, S. M.; Hammerschmidt, P.; Chen, W.; Jais, A.; Timper, K.; Awazawa, M.; Brodesser, S.; Brüning, J. C.: CerS1-derived C18:0 ceramide in skeletal muscle promotes obesity-induced insulin resistance. Cell Reports 26 (1), pp. 1 - 10.e7 (2019)
Journal Article
Wang, L.; De Solis, A. J.; Goffer, Y.; Birkenbach, K. E.; Engle, S. E.; Tanis, R.; Levenson, J. M.; Lie, X.; Rausch, R.; Purohit, M. et al.; Lee, J.-Y.; Tan, J.; De Rosa, M. C.; Doege, C. A.; Aaron, H. L.; Martins, G. J.; Brüning, J. C.; Egli, D.; Costa, R.; Berbari, N.; Leibel, R. L.; Stratigopoulos, G.: Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development. JCI Insight 4, e123337 (2019)
2018
Journal Article
Babaei, R.; Schuster, M.; Meln, I.; Lerch, S.; Ghandour, R. A.; Pisani, D. F.; Bayindir-Buchhalter, I.; Marx, J.; Wu, S.; Schoiswohl, G. et al.; Billeter, A. T.; Krunic, D.; Mauer, J.; Lee, Y.-H.; Granneman, J. G.; Fischer, L.; Mueller-Stich, B. P.; Amri, E.-Z.; Kershaw, E. E.; Heikenwaelder, M.; Herzig, S.; Vegiopoulos, A.: Jak-TGF beta cross-talk links transient adipose tissue inflammation to beige adipogenesis. Science Signaling 11 (527), eaai7838 (2018)
Journal Article
Bender, F.; Korotkova, T.; Ponomarenko, A.: Optogenetic entrainment of hippocampal theta oscillations in behaving mice. Journal of Visualized Experiments 2018 (136), e57349 (2018)
Journal Article
Brandt, C.; Nolte, H.; Henschke, S.; Ruud, L. E.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Günther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krüger, M.; Brüning, J. C.: Food perception primes hepatic ER homeostasis via melanocortin-dependent control of mTOR activation. Cell 175 (5), pp. 1321 - 1335.e.20 (2018)
Journal Article
Choudhary, B.; Mandelkow, E.; Mandelkow, E.-M.; Pir, G. J.: Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation. Neurobiology of Disease 117, pp. 189 - 202 (2018)
Journal Article
Cronin, S. J.F.; Seehus, C.; Weidinger, A.; Talbot, S.; Reissig, S.; Seifert, M.; Pierson, Y.; McNeill, E.; Longhi, M. S.; Lenfers Turnes, B. et al.; Kreslavsky, T.; Kogler, M.; Hoffmann, D.; Ticevic, M.; Da Luz Scheffer, D.; Tortola, L.; Cikes, D.; Jais, A.; Rangachari, M.; Rao, S.; Paolino, M.; Novatchkova, M.; Aichinger, M.; Barrett, L.; Latremoliere, A.; Wirnsberger, G.; Lametschwandtner, G.; Busslinger, M.; Zicha, S.; Latini, A.; Robson, S. C.; Waisman, A.; Andrews, N.; Costigan, M.; Channon, K. M.; Weiss, G.; Kozlov, A. V.; Tebbe, M.; Johnsson, K.; Woolf, C. J.; Penninger, J.: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563 (7732), pp. 564 - 568 (2018)
Journal Article
Dafinger, C.; Rinschen, M. M.; Borgal, L.; Ehrenberg, C.; Basten, S. G.; Franke, M.; Hoehne, M.; Rauh, M.; Goebel, H.; Bloch, W. et al.; Wunderlich, F. T.; Peters, D. J.M.; Tasche, D.; Mishra, T.; Habbig, S.; Dötsch, J.; Müller, R.-U.; Brüning, J. C.; Persigehl, T.; Giles, R. H.; Benzing, T.; Schermer, B.; Liebau, M. C.: Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus. Experimental and Molecular Medicine 50, 75 (2018)
Journal Article
DiFeliceantonio, A.; Coppin, G.; Rigoux, L.; Edwin Thanarajah, S.; Dagher, A.; Tittgemeyer, M.; Small, D. M.: Supra-additive effects of combining fat and carbohydrate on food reward. Cell Metabolism 28 (1), pp. 33 - 44e3 (2018)
Journal Article
Dodd, G. T.; Michael, N. J.; Lee-Young, R. S.; Mangiafico, S. P.; Pryor, J. T.; Munder, A. C.; Simonds, S. E.; Brüning, J. C.; Zhang, Z.-Y.; Cowley, M. A. et al.; Andrikopoulos, S.; Horvath, T. L.; Spanswick, D.; Tiganis, T.: Insulin regulates POMC neuronal plasticity to control glucose metabolism. eLife 7, e38704 (2018)
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Dodd, G. T.; Young, R. S.; Brüning, J. C.; Tiganis, T.: TCPTP regulates insulin signaling in AgRP neurons to coordinate glucose metabolism with feeding. Diabetes 67 (7), pp. 1246 - 1257 (2018)
Journal Article
Ghamari-Langroudi, M.; Cakir, I.; Lippert, R. N.; Sweeney, P.; Litt, M. J.; Ellacott, K. L.J.; Cone, R. D.: Regulation of energy rheostasis by the melanocortin-3 receptor. Science Advances 4 (8), eaat0866 (2018)
Journal Article
Hagelweide, K.; Schönberger, A. R.; Kracht, L. W.; Gründler, T. O. J.; Fink, G. R.; Schubotz, R. I.: Motor cognition in patients treated with subthalamic nucleus deep brain stimulation: Limits of compensatory overactivity in Parkinson's disease. Neuropsychologia 117, pp. 491 - 499 (2018)
Journal Article
Hahn, M.; Buerckert, J.-P.; Luttenberger, C.A.; Klebow, S.; Hess, M.E.; Al-Maarri, M.; Vogt, M. C.; Reißig, S.; Hallek, M.; Wienecke-Baldacchino, A. et al.; Buch, T.; Muller, C.P.; Pallasch, C.P.; Wunderlich, F. T.; Waisman, A.; Hoevelmeyer, N.: Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-kappa B signaling. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 32 (1), pp. 72 - 82 (2018)
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