Publications

Chowdhury, S.; Schulz, L.; Palmisano, B.; Singh, P.; Berger, J. M.; Yadav, V. K.; Mera, P.; Ellingsgaard, H.; Hidalgo, J.; Brüning, J. C. et al.; Karsenty, G.: Muscle-derived interleukin 6 increases exercise capacity by signaling in osteoblasts. Journal of Clinical Investigation 130 (6), pp. 2888 - 2902 (2020)

Ciglieri, E.; Vacca, M.; Ferrini, F.; Atteya, M. A.; Aimar, P.; Ficarra, E.; Cataldo, S. D.; Merighi, A.; Salio, C.: Cytoarchitectural analysis of the neuron-to-glia association in the dorsal root ganglia of normal and diabetic mice. Journal of Anatomy 237 (5), pp. 988 - 997 (2020)

Cole, D. M.; Diaconescu, A. O.; Pfeiffer, U. J.; Brodersen, K. H.; Mathys, C. D.; Julkowski, D.; Ruhrmann, S.; Schilbach, L.; Tittgemeyer, M.; Vogeley, K. et al.; Stephan, K. E.: Atypical processing of uncertainty in individuals at risk for psychosis. NeuroImage: Clinical 26, 102239 (2020)

Ding, X.; Willenborg, S.; Bloch, W.; Wickström, S. A.; Wagle, P.; Brodesser, S.; Roers, A.; Jais, A.; Brüning, J. C.; Hall, M. N. et al.; Rüegg, M. A.; Eming, S. A.: Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. Journal of Allergy and Clinical Immunology 145 (1), pp. 283 - 300.e8 (2020)

DiToro, D.; Harbour, S. N.; Brando, J. K.; Benavides, G.; Witte, S.; Laufer, V. A.; Moseley, C.; Singer, J. R.; Frey, B.; Turner, H. et al.; Brüning, J. C.; Darley-Usmar, V.; Gao, M.; Conover, C.; Hatton, R. D.; Frank, S.; Colonna, M.; Weaver, C. T.: Insulin-Like growth factors are key regulators of T helper 17 regulatory T cell balance in autoimmunity. Immunity 52 (4), pp. 650 - 667 (2020)

Ellingsgaard, H.; Seelig, E.; Timper, K.; Coslovsky, M.; Soederlund, L.; Lyngbaek, M. P.; Albrechtsen, N. J. W.; Schmidt-Trucksass, A.; Hanssen, H.; Frey, W. O. et al.; Karstoft, K.; Pedersen, B. K.; Boni-Schnetzler, M.; Donath, M. Y.: GLP-1 secretion is regulated by IL-6 signalling: a randomised, placebo-controlled study. Diabetologia 63 (2), pp. 362 - 373 (2020)

Fischer, K.; Fenzl, A.; Liu, D.; Dyar, K. A.; Kleinert, M.; Brielmeier, M.; Clemmensen, C.; Fedl, A.; Finan, B.; Gessner, A. et al.; Jastroch, M.; Huang, J.; Keipert, S.; Klingenspor, M.; Brüning, J. C.; Kneilling, M.; Maier, F. C.; Othman, A. E.; Pichler, B. J.; Pramme-Steinwachs, I.; Sachs, S.; Scheideler, A.; Thaiss, W. M.; Uhlenhaut, H.; Ussar, S.; Woods, S. C.; Zorn, J.; Stemmer, K.; Collins, S.; Diaz-Meco, M.; Moscat, J.; Tschöp, M. H.; Müller, T. D.: The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. Nature Communications 11 (1), 2306 (2020)

Heikenfeld, C.; Mederos, S.; Chen, C.; Korotkova, T.; Schnitzler, A.; Ponomarenko, A.: Prefrontal - subthalamic pathway supports action selection in a spatial working memory task. Scientific Reports 10 (1), 10497 (2020)

Jais, A.; Paeger, L.; Sotelo-Hitschfeld, T.; Bremser, S.; Prinzensteiner, M.; Klemm, P.; Mykytiuk, V.; Widdershooven, P. J.M.; Vesting, A. J.; Grzelka, K. et al.; Minère, M.; Cremer, A. L.; Xu, J.; Korotkova, T.; Lowell, B. B.; Zeilhofer, H. U.; Fenselau, H.; Backes, H.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding. Neuron 106 (6), pp. 1009 - 1025.e10 (2020)

Jiang, H.; Gallet, S.; Klemm, P.; Scholl, P.; Folz-Donahue, K.; Altmüller, J.; Alber, J.; Heilinger, C.; Kukat, C.; Loyens, A. et al.; Müller-Fielitz, H.; Sundaram, S.; Schwaninger, M.; Prevot, V.; Brüning, J. C.: MCH neurons regulate permeability of the median eminence barrier. Neuron 107 (2), pp. 306 - 319.e9 (2020)

Koch, C.E.; Begemann, K.; Kiehn, J.T.; Griewahn, L.; Mauer, J.; Heß, M. E.; Moser, A.; Schmid, S.M.; Brüning, J. C.; Oster, H.: Circadian regulation of hedonic appetite in mice by clocks in dopaminergic neurons of the VTA. Nature Communications 11 (1), 3071 (2020)

Lippert, R. N.; Hess, S.; Klemm, P.; Burgeno, L. M.; Jahans-Price, T.; Walton, M. E.; Kloppenburg, P.; Brüning, J. C.: Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice. Journal of Clinical Investigation (New York, NY) 130 (7), pp. 3761 - 3776 (2020)

Mittenbühler, M.; Saedler, K.; Nolte, H.; Kern, L.; Zhou, J.; Qian, S.-B.; Meder, L.; Ullrich, R. T.; Brüning, J. C.; Wunderlich, F. T.: Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo. Molecular Metabolism 42, 101085 (2020)

Pradas-Juni, M.; Hansmeier, N. R.; Link, J. C.; Schmidt, E.; Larsen , B. D.; Klemm, P.; Meola, N.; Topel, H.; Loureiro, R.; Dhaouadi, I. et al.; Kiefer, C. A.; Schwarzer, R.; Khani, S.; Oliverio, M.; Awazawa, M.; Frommolt, P.; Heeren, J.; Scheja, L.; Heine, M.; Dieterich, C.; Büning, H.; Yang, L.; Cao, H.; De Jesus, D. F.; Kulkarni, R. N.; Zevnik, B.; Tröder, S. E.; Knippschild, U.; Edwards, P. A.; Lee, R. G.; Yamamoto, M.; Ulitsky, I.; Fernandez-Rebollo, E.; Vallim, T. Q. d. A.; Kornfeld, J.-W.: A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Nature Communications 11 (1), 644 (2020)

Ruud, L. E.; Pereira, M. M.; de Solis, A.; Fenselau, H.; Brüning, J. C.: NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons. Nature Communications 11 (1), 442 (2020)

Sevgi, M.; Diaconescu, A. O.; Henco, L.; Tittgemeyer, M.; Schilbach, L.: Social Bayes: Using Bayesian modeling to study autistic trait–related differences in social cognition. Biological Psychiatry 87 (2), pp. 185 - 193 (2020)

Timper, K.; Del Rio-Martin, A.; Cremer, A. L.; Bremser, S.; Alber, J.; Giavalisco, P.; Varela, L.; Heilinger, C.; Nolte, H.; Trifunovic, A. et al.; Horvath, T. L.; Kloppenburg, P.; Backes, H.; Brüning, J. C.: GLP-1 receptor signaling in astrocytes regulates fatty acid oxidation, mitochondrial integrity, and function. Cell Metabolism 31 (6), pp. 1189 - 1205.e13 (2020)

Turpin-Nolan, S. M.; Brüning, J. C.: The role of ceramides in metabolic disorders: when size and localization matters. Nature Reviews Endocrinology 16 (4), pp. 224 - 233 (2020)