Publications

Baris, O. R.; Ederer, S.; Neuhaus , J. F. G.; von Kleist-Retzow, J.-C.; Wunderlich, C.; Pal, M.; Wunderlich, F. T.; Peeva, V.; Zsurka, G.; Kunz , W. S. et al.; Hickethier, T.; Bunck, A. C.; Stöckigt, F.; Schrickel, J. W.; Wiesner , R. J.: Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging. Cell Metabolism 21 (6), pp. 667 - 677 (2015)

Carter, D. R.; Murray , J.; Cheung, B. B.; Gamble, L.; Koach, J.; Tsang, J.; Sutton, S.; Kalla, H.; Syed, S.; Gifford, A. J. et al.; Issaeva, N.; Biktasova, A.; Atmadibrata, B.; Sun, Y.; Sokolowski, N.; Ling, D.; Kim, P. Y.; Webber, H.; Clark, A.; Ruhle, M.; Liu, B.; Oberthuer, A.; Fischer, M.; Byrne, J.; Saletta, F.; Thwe, L. M.; Purmal, A.; Haderski, G.; Burkhart, C.; Speleman, F.; De Preter, K.; Beckers, A.; Ziegler, D. S.; Liu, T.; Gurova, K.; Gudkov, A. V.; Norris, M. D.; Haber, M.; Marshall, G. M.: Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma. Science Translational Medicine 7 (312), 312ra176 (2015)

Fey, D.; Halasz, M.; Dreidax, D.; Kennedy, S. P.; Hastings, J. F.; Rauch, N.; Munoz, A. G.; Pilkington, R.; Fischer, M.; Westermann, F. et al.; Kolch, W.; Kholodenko, B. N.; Croucher, D. R.: Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients. Science Signaling 8 (408), ra130 (2015)

Knuever, J.; Willenborg, S.; Ding, X.; Akyuez, M. D.; Partridge, L.; Niessen, C. M.; Brüning, J. C.; Eming, S.: Myeloid cell-restricted insulin/IGF-1 receptor deficiency protects against skin inflammation. Journal of Immunology 195 (11), pp. 5296 - 5308 (2015)

Oster, H.; Brüning, J. C.; Lehnert, H.: Transregionaler Sonderforschungsbereich 134: "Ingestive Behaviour: Homeostasis & Reward". Neuroforum 21 (2), pp. 74 - 77 (2015)

Peters, F.; Vorhagen, S.; Brodesser, S.; Jakobshagen, K.; Brüning, J. C.; Niessen, C. M.; Krönke, M.: Ceramide synthase 4 regulates stem cell homeostasis and hair follicle cycling. Journal of Investigative Dermatology 135 (6), pp. 1501 - 1509 (2015)

Ruud, J.; Brüning, J. C.: Metabolism: Light on leptin link to lipolysis. Nature 527 (7576), pp. 43 - 44 (2015)

Schönberger, A. R.; Hagelweide, K.; Pelzer, E. A.; Fink, G. R.; Schubotz, R. I.: Motor loop dysfunction causes impaired cognitive sequencing in patients suffering from Parkinson's diseas. Neuropsychologia 77, 5729, pp. 409 - 420 (2015)

Sevgi, M.; Rigoux, L.; Kühn, A. B.; Mauer, J.; Schilbach, L.; Heß, M. E.; Gründler, T. O. J.; Ullsperger, M.; Stephan, K. E.; Brüning, J. C. et al.; Tittgemeyer, M.: An obesity-predisposing variant of the FTO gene regulates D2R-dependent reward learning. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 35 (36), pp. 12584 - 12592 (2015)

Steculorum, S. M.; Paeger, L.; Bremser, S.; Evers, N.; Hinze, Y.; Idzko, M.; Kloppenburg, P.; Brüning, J. C.: Hypothalamic UDP increases in obesity and promotes feeding via P2Y6-dependent activation of AgRP neurons. Cell 162 (6), pp. 1404 - 1417 (2015)

Timper, K.; Seelig, E.; Tsakiris, D. A.; Donath, M. Y.: Safety, pharmacokinetics, and preliminary efficacy of a specific anti-IL-1alpha therapeutic antibody (MABp1) in patients with type 2 diabetes mellitus. Journal of Diabetes and Its Complications 29 (7), pp. 955 - 960 (2015)

Volz, L. J.; Sarfeld, A.-S.; Diekhoff, S.; Rehme, A. K.; Pool, E.-M.; Eickhoff, S. B.; Fink, G. R.; Grefkes, C.: Motor cortex excitability and connectivity in chronic stroke: a multimodal model of functional reorganization. Brain Structure and Function 220 (2), pp. 1093 - 1107 (2015)