Publications

Babaei, R.; Schuster, M.; Meln, I.; Lerch, S.; Ghandour, R. A.; Pisani, D. F.; Bayindir-Buchhalter, I.; Marx, J.; Wu, S.; Schoiswohl, G. et al.; Billeter, A. T.; Krunic, D.; Mauer, J.; Lee, Y.-H.; Granneman, J. G.; Fischer, L.; Mueller-Stich, B. P.; Amri, E.-Z.; Kershaw, E. E.; Heikenwaelder, M.; Herzig, S.; Vegiopoulos, A.: Jak-TGF beta cross-talk links transient adipose tissue inflammation to beige adipogenesis. Science Signaling 11 (527), eaai7838 (2018)

Bender, F.; Korotkova, T.; Ponomarenko, A.: Optogenetic entrainment of hippocampal theta oscillations in behaving mice. Journal of Visualized Experiments 2018 (136), e57349 (2018)

Brandt, C.; Nolte, H.; Henschke, S.; Ruud, L. E.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Günther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krüger, M.; Brüning, J. C.: Food perception primes hepatic ER homeostasis via melanocortin-dependent control of mTOR activation. Cell 175 (5), pp. 1321 - 1335.e.20 (2018)

Choudhary, B.; Mandelkow, E.; Mandelkow, E.-M.; Pir, G. J.: Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation. Neurobiology of Disease 117, pp. 189 - 202 (2018)

Cronin, S. J.F.; Seehus, C.; Weidinger, A.; Talbot, S.; Reissig, S.; Seifert, M.; Pierson, Y.; McNeill, E.; Longhi, M. S.; Lenfers Turnes, B. et al.; Kreslavsky, T.; Kogler, M.; Hoffmann, D.; Ticevic, M.; Da Luz Scheffer, D.; Tortola, L.; Cikes, D.; Jais, A.; Rangachari, M.; Rao, S.; Paolino, M.; Novatchkova, M.; Aichinger, M.; Barrett, L.; Latremoliere, A.; Wirnsberger, G.; Lametschwandtner, G.; Busslinger, M.; Zicha, S.; Latini, A.; Robson, S. C.; Waisman, A.; Andrews, N.; Costigan, M.; Channon, K. M.; Weiss, G.; Kozlov, A. V.; Tebbe, M.; Johnsson, K.; Woolf, C. J.; Penninger, J.: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563 (7732), pp. 564 - 568 (2018)

Dafinger, C.; Rinschen, M. M.; Borgal, L.; Ehrenberg, C.; Basten, S. G.; Franke, M.; Hoehne, M.; Rauh, M.; Goebel, H.; Bloch, W. et al.; Wunderlich, F. T.; Peters, D. J.M.; Tasche, D.; Mishra, T.; Habbig, S.; Dötsch, J.; Müller, R.-U.; Brüning, J. C.; Persigehl, T.; Giles, R. H.; Benzing, T.; Schermer, B.; Liebau, M. C.: Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus. Experimental and Molecular Medicine 50, 75 (2018)

DiFeliceantonio, A.; Coppin, G.; Rigoux, L.; Edwin Thanarajah, S.; Dagher, A.; Tittgemeyer, M.; Small, D. M.: Supra-additive effects of combining fat and carbohydrate on food reward. Cell Metabolism 28 (1), pp. 33 - 44e3 (2018)

Dodd, G. T.; Michael, N. J.; Lee-Young, R. S.; Mangiafico, S. P.; Pryor, J. T.; Munder, A. C.; Simonds, S. E.; Brüning, J. C.; Zhang, Z.-Y.; Cowley, M. A. et al.; Andrikopoulos, S.; Horvath, T. L.; Spanswick, D.; Tiganis, T.: Insulin regulates POMC neuronal plasticity to control glucose metabolism. eLife 7, e38704 (2018)

Dodd, G. T.; Young, R. S.; Brüning, J. C.; Tiganis, T.: TCPTP regulates insulin signaling in AgRP neurons to coordinate glucose metabolism with feeding. Diabetes 67 (7), pp. 1246 - 1257 (2018)

Ghamari-Langroudi, M.; Cakir, I.; Lippert, R. N.; Sweeney, P.; Litt, M. J.; Ellacott, K. L.J.; Cone, R. D.: Regulation of energy rheostasis by the melanocortin-3 receptor. Science Advances 4 (8), eaat0866 (2018)

Hagelweide, K.; Schönberger, A. R.; Kracht, L. W.; Gründler, T. O. J.; Fink, G. R.; Schubotz, R. I.: Motor cognition in patients treated with subthalamic nucleus deep brain stimulation: Limits of compensatory overactivity in Parkinson's disease. Neuropsychologia 117, pp. 491 - 499 (2018)

Hahn, M.; Buerckert, J.-P.; Luttenberger, C.A.; Klebow, S.; Hess, M.E.; Al-Maarri, M.; Vogt, M. C.; Reißig, S.; Hallek, M.; Wienecke-Baldacchino, A. et al.; Buch, T.; Muller, C.P.; Pallasch, C.P.; Wunderlich, F. T.; Waisman, A.; Hoevelmeyer, N.: Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-kappa B signaling. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 32 (1), pp. 72 - 82 (2018)

Jiang, H.; Brüning, J. C.: Melanin-concentrating hormone-dependent control of feeding: when volume matters. Cell Metabolism 28 (1), pp. 7 - 8 (2018)

Korotkova, T.; Ponomarenko, A.; Monaghan, C. K.; Poulter, S. L.; Cacucci, F.; Wills, T.; Hasselmo, M. E.; Lever, C.: Reconciling the different faces of hippocampal theta: The role of theta oscillations in cognitive, emotional and innate behaviors. Neuroscience and Biobehavioral Reviews 85, pp. 65 - 80 (2018)

Löhr, H.; Hess, S.; Robalo de Azevedo Aleixo Pereira, M. M.; Reinoß, P.; Leibold, S.; Schenkel, C.; Wunderlich, C. M.; Kloppenburg, P.; Brüning, J. C.; Hammerschmidt, M.: Diet-induced growth is regulated via acquired Leptin resistance and engages a Pomc-somatostatin-growth hormone circuit. Cell Reports 23 (6), pp. 1728 - 1741 (2018)

Mittenbühler, M.; Sprenger, H.-G.; Gruber, S.; Wunderlich, C. M.; Kern, L.; Brüning, J. C.; Wunderlich, F. T.: Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma. Molecular Metabolism 17, pp. 122 - 133 (2018)

Ponomarenko, A.; Korotkova, T.: Hunger is a gatekeeper of pain in the brain. Nature 556 (7702), pp. 445 - 446 (2018)

Quinones, M.; Al-Massadi, O.; Folgueira, C.; Bremser, S.; Gallego, R.; Torres-Leal, L.; Haddad-Tovolli, R.; Carcia-Caceres, C.; Hernandez-Bautista, R.; Lam, B. Y.H. et al.; Beiroa, D.; Sanchez-Rebordelo, E.; Senra, A.; Malagon, J. A.; Valeria, P.; Fondevila, M. F.; Ferno, J.; Malagon, M. M.; Contreras, R.; Pfluger, P.; Brüning, J. C.; Yeo, G.; Tschöp, M. H.; Dieguez, C.; Lopez, M.; Claret, M.; Kloppenburg, P.; Sabio, G.; Nogueiras, R.: p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1. Nature Communications 9 (1), 3432 (2018)

Schmidt, E.; Dhaouadi, I.; Gaziano, I.; Oliverio, M.; Klemm, P.; Awazawa, M.; Mitterer, G.; Fernandez-Rebollo, E.; Pradas-Juni, M.; Wagner, W. et al.; Hammerschmidt, P.; Loureiro, R.; Kiefer, C.; Hansmeier, N. R.; Frommolt, P.; Zentis, P.; Orom, U. A.; Heeren, J.; Blüher, M.; Bilban, M.; Kornfeld, J.-W.: LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat. Nature Communications 9, 3622 (2018)

Schüler, R.; Seebeck, N.; Osterhoff, M. A.; Witte, V.; Flöel, A.; Busjahn, A.; Jais, A.; Brüning, J. C.; Frahnow, T.; Kabisch, S. et al.; Pivovarova, O.; Hornemann, S.; Kruse, M.; Pfeiffer, A. F.H.: VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humans. Molecular Metabolism 11 (May), pp. 129 - 136 (2018)