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Open Positions

Upcoming Talks and Events

February 2019
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Talk by Prof. Ana Domingos, University of Oxford

from 16:00 to 17:00

 21 22 23 24
25
Talk by Prof. Tune Hannes Peers, University of Copenhagen

from 14:00 to 15:15

 26 27 28

Snapshots

Institute main building (porter's lodge)

Our research interest focuses on regeneration of cerebral lesions, in particular stroke. We pursue the goal of regeneration through implantation of (neural) stem cells and thereby explore their therapeutic potential.

LncRNAs and Glucose Homeostasis (Kornfeld)

The Central Nervous System (CNS) is constantly instructed about the energy state of the organism via hormonal and nutritional signals. It then coordinately regulates a wide array of behavioral and autonomic responses to adapt energy intake, energy expenditure, and nutrient flux across different organs, according to energy availability of the organism. Dysregulation of these homeostatic circuits causes prevalent diseases, such as obesity and type-2 diabetes mellitus, which are on an epidemic rise in industrialized societies. The overall aim of our research group is to unravel the fundamental regulatory principles of how neurons sense nutritional cues and then to determine the neurocircuitry responsible for the coordinated adaptation of behavioral and autonomic outputs. Moreover, we aim to identify molecular and physiological mechanisms for alterations in these pathways during the development of obesity and type-2 diabetes mellitus. Finally, we are also investigating the molecular basis of how genetic variants link with obesity as well as how metabolic disorders affect these fundamental regulatory principles. The ultimate aim of our research is to discover novel therapeutic targets for the development of treatment of metabolic disorders.

In the lab

The Multimodal Imaging of Brain Metabolism group combines invasive and non-invasive methods for the in vivo assessment of brain metabolism to study brain function under both healthy and pathological conditions. For this purpose, we use a dedicated small animal positron emission tomography (PET) and µCT scanner, which we combine with laser speckle imaging LSI, RGB reflectometry, rapid sampling microdialysis, and electrophysiological methods. In close collaboration with the in vivo NMR group, we provide a portfolio of cutting-edge in vivo imaging modalities that are also integral to research projects of several other groups at the MPI for Metabolism Research. In addition, we also perform clinical studies using a dedicated brain PET scanner and, in collaboration with the translational neurocircuitry group, MRI. Our research activities cover three major topics: 1. defining demand-related regulation of brain energy metabolism2. identifying network activations3. understanding altered regulation of brain metabolism in pathological conditions.

DREADDS (Multimodal Imaging)

News
Apply now for our Ph.D. positions starting from July until October 2019! Application deadline: January 07, 2019.

Apply now!

Apply now for our Ph.D. positions starting from July until October 2019! Application deadline: January 07, 2019.

The Max Planck Institute for Metabolism Research

Maintenance of energy homeostasis, i.e. the balance between caloric intake and energy expenditure, has to be maintained in a tight range to ensure metabolic homeostasis, health, and survival of any organism. Throughout evolution, a sophisticated neuronal network has developed... [more]
350 guests visited the MPI for Metabolism Research on Friday, September 14 2018 to get a first-hand impression of research topics and labs.You can find a detailed report about the Max Planck Day with some images here:

Max Planck Day 2018

350 guests visited the MPI for Metabolism Research on Friday, September 14 2018 to get a first-hand impression of research topics and labs.

You can find a detailed report about the Max Planck Day with some images here: [more]
It is time for us to celebrate our ERC grant holders!We will release one Youtube-clip per day about the researchers and their projects.

ERC-Week

March 16, 2017

It is time for us to celebrate our ERC grant holders!

We will release one Youtube-clip per day about the researchers and their projects.
 
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