Department Brüning

Journal Article (185)

2020
Journal Article
Heikenfeld, C.; Mederos, S.; Chen, C.; Korotkova, T.; Schnitzler, A.; Ponomarenko, A.: Prefrontal - subthalamic pathway supports action selection in a spatial working memory task. Scientific Reports 10 (1), 10497 (2020)
Journal Article
Jais, A.; Paeger, L.; Sotelo-Hitschfeld, T.; Bremser, S.; Prinzensteiner, M.; Klemm, P.; Mykytiuk, V.; Widdershooven, P. J.M.; Vesting, A. J.; Grzelka, K. et al.; Minère, M.; Cremer, A. L.; Xu, J.; Korotkova, T.; Lowell, B. B.; Zeilhofer, H. U.; Fenselau, H.; Backes, H.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding. Neuron 106 (6), pp. 1009 - 1025.e10 (2020)
Journal Article
Jiang, H.; Gallet, S.; Klemm, P.; Scholl, P.; Folz-Donahue, K.; Altmüller, J.; Alber, J.; Heilinger, C.; Kukat, C.; Loyens, A. et al.; Müller-Fielitz, H.; Sundaram, S.; Schwaninger, M.; Prevot, V.; Brüning, J. C.: MCH neurons regulate permeability of the median eminence barrier. Neuron 107 (2), pp. 306 - 319.e9 (2020)
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Koch, C.E.; Begemann, K.; Kiehn, J.T.; Griewahn, L.; Mauer, J.; Heß, M. E.; Moser, A.; Schmid, S.M.; Brüning, J. C.; Oster, H.: Circadian regulation of hedonic appetite in mice by clocks in dopaminergic neurons of the VTA. Nature Communications 11 (1), 3071 (2020)
Journal Article
Lippert, R. N.; Hess, S.; Klemm, P.; Burgeno, L. M.; Jahans-Price, T.; Walton, M. E.; Kloppenburg, P.; Brüning, J. C.: Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice. Journal of Clinical Investigation (New York, NY) 130 (7), pp. 3761 - 3776 (2020)
Journal Article
Mittenbühler, M.; Saedler, K.; Nolte, H.; Kern, L.; Zhou, J.; Qian, S.-B.; Meder, L.; Ullrich, R. T.; Brüning, J. C.; Wunderlich, F. T.: Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo. Molecular Metabolism 42, 101085 (2020)
Journal Article
Pradas-Juni, M.; Hansmeier, N. R.; Link, J. C.; Schmidt, E.; Larsen , B. D.; Klemm, P.; Meola, N.; Topel, H.; Loureiro, R.; Dhaouadi, I. et al.; Kiefer, C. A.; Schwarzer, R.; Khani, S.; Oliverio, M.; Awazawa, M.; Frommolt, P.; Heeren, J.; Scheja, L.; Heine, M.; Dieterich, C.; Büning, H.; Yang, L.; Cao, H.; De Jesus, D. F.; Kulkarni, R. N.; Zevnik, B.; Tröder, S. E.; Knippschild, U.; Edwards, P. A.; Lee, R. G.; Yamamoto, M.; Ulitsky, I.; Fernandez-Rebollo, E.; Vallim, T. Q. d. A.; Kornfeld, J.-W.: A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Nature Communications 11 (1), 644 (2020)
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Ruud, L. E.; Pereira, M. M.; de Solis, A.; Fenselau, H.; Brüning, J. C.: NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons. Nature Communications 11 (1), 442 (2020)
Journal Article
Sevgi, M.; Diaconescu, A. O.; Henco, L.; Tittgemeyer, M.; Schilbach, L.: Social Bayes: Using Bayesian modeling to study autistic trait–related differences in social cognition. Biological Psychiatry 87 (2), pp. 185 - 193 (2020)
Journal Article
Timper, K.; Del Rio-Martin, A.; Cremer, A. L.; Bremser, S.; Alber, J.; Giavalisco, P.; Varela, L.; Heilinger, C.; Nolte, H.; Trifunovic, A. et al.; Horvath, T. L.; Kloppenburg, P.; Backes, H.; Brüning, J. C.: GLP-1 receptor signaling in astrocytes regulates fatty acid oxidation, mitochondrial integrity, and function. Cell Metabolism 31 (6), pp. 1189 - 1205.e13 (2020)
Journal Article
Turpin-Nolan, S. M.; Brüning, J. C.: The role of ceramides in metabolic disorders: when size and localization matters. Nature Reviews Endocrinology 16 (4), pp. 224 - 233 (2020)
2019
Journal Article
Cheng, Y.; Luo, H.; Izzo, F.; Pickering, B. F.; Nguyen, D.; Myers, R.; Schurer, A.; Gourkanti, S.; Brüning, J. C.; Vu, L. P. et al.; Landau, D. A.; Kharas, M. G.: m6A RNA methylation maintains hematopoietic stem cell identity and symmetric commitment. Cell Reports 28 (7), pp. P1703 - P1716.e6 (2019)
Journal Article
Edwin Thanarajah, S.; Iglesias, S.; Kuzmanovic, B.; Rigoux, L.; Stephan, K. E.; Brüning, J. C.; Tittgemeyer, M.: Modulation of midbrain neurocircuitry by intranasal insulin. NeuroImage 194, pp. 120 - 127 (2019)
Journal Article
Hammerschmidt, P.; Ostkotte, D.; Nolte, H.; Gerl, M. J.; Jais, A.; Brunner, H. L.; Sprenger, H.-G.; Awazawa, M.; Nicholls, H. T.; Turpin-Nolan, S. M. et al.; Langer, T.; Krüger, M.; Brügger, B.; Brüning, J. C.: CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity. Cell 177 (6), pp. 1536 - 1552.e23 (2019)
Journal Article
Ip, C. K.; Zhang, L.; Farzi, A.; Qi, Y.; Clarke, I.; Reed, F.; Shi, Y.-C.; Enriquez, R.; Dayas , C.; Graham, B. et al.; Begg, D.; Brüning, J. C.; Lee, N. J.; Hernandez-Sanchez, D.; Gopalasingam, G.; Koller, J.; Tasan, R.; Sperk, G.; Herzog, H.: Amygdala NPY circuits promote the development of accelerated obesity under chronic stress conditions. Cell Metabolism 30 (1), pp. 111 - 128.e6 (2019)
Journal Article
Koach, J.; Holien, J. K.; Massudi, H.; Carter, D. R.; Ciampa, O. C.; Herath, M.; Lim, T.; Seneviratne, J. A.; Milazzo, G.; Murray, J. E. et al.; McCarroll, J. A.; Liu, B.; Mayoh, C.; Keenan, B.; Stevenson, B. W.; Gorman, M. A.; Bell, J. L.; Doughty, L.; Hüttelmaier, S.; Oberthuer, A.; Fischer, M.; Gifford, A. J.; Liu, T.; Zhang, X.; Zhu, S.; Gustafson, W. C.; Haber, M.; Norris, M. D.; Fletcher, J. I.; Perini, G.; Parker, M. W.; Cheung, B. B.; Marshall, G. M.: Drugging MYCN oncogenic signaling through the MYCN-PA2G4 binding interface. Cancer Research: an official organ of the American Association for Cancer Research 79 (21), pp. 5652 - 5667 (2019)
Journal Article
Lippert, R. N.; Cremer, A. L.; Thanarajah, S. E.; Korn, C.; Jahans-Price, T.; Burgeno, L. M.; Tittgemeyer, M.; Brüning, J. C.; Walton, M. E.; Backes, H.: Time-dependent assessment of stimulus-evoked regional dopamine release. Nature Communications 10 (1), 336 (2019)
Journal Article
MacVicar, T.; Ohba, Y.; Nolte, H.; Mayer, F. C.; Tatsuta, T.; Sprenger, H.-G.; Lindner, B.; Zhao, Y.; Li, J.; Bruns, C. et al.; Krüger, M.; Habich, M.; Riemer, J.; Schwarzer, R.; Pasparakis, M.; Henschke, S.; Brüning, J. C.; Zamboni, N.; Langer, T.: Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature 575 (7782), pp. 361 - 365 (2019)
Journal Article
Ostermann, A. L.; Wunderlich, C. M.; Schneiders, L.; Vogt, M. C.; Woeste, M.A.; Belgardt, B. F.; Niessen, C. M.; Martiny, B.; Schauss, A. C.; Frommolt, P. et al.; Nikolaev, A.; Hövelmeyer, N.; Sears, R.C.; Koch, P.J.; Günzel, D.; Brüning, J. C.; Wunderlich, F. T.: Intestinal insulin/IGF1 signalling through FoxO1 regulates epithelial integrity and susceptibility to colon cancer. Nature Metabolism 1 (3), pp. 371 - 389 (2019)
Journal Article
Pelzer, E. A.; Melzer, C.; Schönberger, A. R.; Heß, M. E.; Timmermann, L.; Eggers, C.; Tittgemeyer, M.: Axonal degeneration in Parkinson's disease – Basal ganglia circuitry and D2 receptor availability. NeuroImage: Clinical 23, 101906 (2019)
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