Seminare und Veranstaltungen

The design and function of endocrine systems follows an intrinsic logic that is not specific, but widely present in physiology. In my talk, I discuss homeostatic circuit designs at the intersection of endocrinology and immunology. I highlight examples that align with this regulatory principle and those that may not. I then address the potential connection between homeostatic control and inflammation and touch upon how I have applied this framework to one of my projects on cancer. I summarize my more recent findings on pharmacological manipulation of neuroendocrine control of leukocyte compartments that I approached from the same perspective, followed by a discussion of my observations in a broader context. Finally, I provide insights into fields that I am currently thinking about and actively pursuing, which have naturally emerged as a consequence of my scientific trajectory. I close my talk with concluding remarks and potential future avenues for scientific discovery. [mehr]

Obesity is intertwined with behaviour. Many eating-related behaviours have been proposed to explain obesity, such as food addiction, disinhibition and emotional eating. However, these behaviours tend to similarities based on both statistics and definitions. I propose that these behaviours can be aggregated into a single broad trait – Uncontrolled Eating. Such an approach enables reviewing and meta‐analysing evidence done on each individual behaviour. I review evidence how the aggregated Uncontrolled Eating has robust associations with body mass index, food intake, personality traits, and brain systems. I also map out Uncontrolled Eating’s behavioural similarity with other addictions and psychiatric conditions. In summary, Uncontrolled Eating summarises important behavioural aspects of obesity. [mehr]

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