Synaptic Transmission in Energy Homeostasis Group
The goal of our research is to link synaptic transmission and synaptic adaptions with specific metabolic responses and behavior. To address this question, we employ a wide range of methodologies including: Brain slice electrophysiology, optogenetics, chemogenetics, transgenic knockin and knockout mice, AAV viral approaches, in vivo imaging and morphological methods. The combination of these approaches allows us to study neurotransmitters, synaptic plasticity, and activity patterns in defined circuit elements. Furthermore, they also enable us to understand how synaptic adaptions within these neural circuits could become dysregulated in conditions such as obesity or diabetes.