Department Brüning

Journal Article (185)

2016
Journal Article
Schmitz, J.; Evers, N.; Awazawa, M.; Nicholls, H. T.; Brönneke, H. S.; Dietrich, A.; Mauer, J.; Blüher, M.; Brüning, J. C.: Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss. Molecular Metabolism 5 (5), pp. 328 - 339 (2016)
Journal Article
Sevgi, M.; Diaconescu, A. O.; Tittgemeyer, M.; Schilbach, L.: Social Bayes: Using Bayesian modeling to study autistic trait-related differences in social cognition. Biological Psychiatry 80 (2), pp. 112 - 119 (2016)
Journal Article
Steculorum, S. M.; Brüning, J. C.: Sweet mitochondrial dynamics in VMH neurons. Cell Metabolism 23 (4), pp. 577 - 579 (2016)
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Steculorum, S. M.; Ruud, J.; Karakasilioti, I.; Backes, H.; Engström Ruud, L.; Timper, K.; Heß, M. E.; Tsaousidou, E.; Mauer, J.; Vogt, M. C. et al.; Paeger, L.; Bremser, S.; Klein, A. C.; Morgan, D. A.; Frommolt, P.; Brinkkötter, P. T.; Hammerschmidt, P.; Benzing, T.; Rahmouni, K.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue. Cell 165 (1), pp. 125 - 138 (2016)
Journal Article
Theurich, S.; Rothschild, S. I.; Hoffmann, M.; Fabri, M.; Sommer, A.; Garcia-Marquez, M. A.; Thelen, M.; Schill, C.; Merki, R.; Schmid, T. et al.; Koeberle, D.; Zippelius, A.; Baues, C.; Mauch, C.; Tigges, C.; Kreuter, A.; Borggrefe, J.; von Bergwelt-Baildon, M.; Schlaak, M.: Local tumor treatment in combination with systemic ipilimumab immunotherapy prolongs overall survival in patients with advanced malignant melanoma. Cancer Immunology Research 4 (9), pp. 744 - 754 (2016)
Journal Article
Urwyler, S. A.; Timper, K.; Fenske, W.; De Mota, N.; Blanchard, A.; Kühn, F.; Frech, N.; Arici, B.; Rutishauser, J.; Kopp, P. et al.; Stettler, C.; Müller, B.; Katan, M.; Llorens-Cortes, C.; Christ-Crain, M.: Plasma apelin concentrations in patients with polyuria-polydipsia syndrome. Journal of Clinical Endocrinology and Metabolism 101 (5), pp. 1917 - 1923 (2016)
Journal Article
Wilhelm, K.; Happel, K.; Eelen, G.; Schoors, S.; Oellerich, M. F.; Lim, R.; Zimmermann, B.; Aspalter, I. M.; Franco, C. A.; Boettger, T. et al.; Braun, T.; Fruttiger, M.; Rajewsky, K.; Keller, C.; Brüning, J. C.; Gerhardt, H.; Carmeliet, P.; Potente, M.: FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature 529 (7585), pp. 216 - 220 (2016)
Journal Article
Worst, B. C.; van Tilburg, C.; Balasubramanian, G. P.; Fiesel, P.; Witt, R.; Freitag, A.; Boudalil, M.; Previti, C.; Wolf, S.; Schmidt, S. et al.; Chotewutmontri, S.; Bewerunge-Hudler, M.; Schick, M.; Schlesner, M.; Hutter, B.; Taylor, L.; Borst, T.; Sutter, C.; Bartram, C. R.; Milde, T.; Pfaff, E.; Kulozik, A. E.; von Stackelberg, A.; Meisel, R.; Borkhardt, A.; Reinhardt, D.; Klusmann, J.-H.; Fleischhack, G.; Tippelt, S.; Dirksen, U.; Jürgens, H.; Kramm, C. M.; von Bueren, A. O.; Westermann, F.; Fischer, M.; Burkhardt, B.; Wößmann, W.; Nathratha, M.; Bielacka, S. S.; Frühwald, M. C.; Fulda, S.; Klingebiel, T.; Koscielniak, E.; Schwab, M.; Tremmel, R.; Driever, P. H.; Schulte, J. H.; Brors, B.; von Deimling, A.; Lichter, P.; Eggert, A.; Capper, D.; Pfister, S. M.; Jones, D. T.W.; Witt, O.: Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study. European Journal of Cancer 65, pp. 91 - 101 (2016)
2015
Journal Article
Baris, O. R.; Ederer, S.; Neuhaus , J. F. G.; von Kleist-Retzow, J.-C.; Wunderlich, C.; Pal, M.; Wunderlich, F. T.; Peeva, V.; Zsurka, G.; Kunz , W. S. et al.; Hickethier, T.; Bunck, A. C.; Stöckigt, F.; Schrickel, J. W.; Wiesner , R. J.: Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging. Cell Metabolism 21 (6), pp. 667 - 677 (2015)
Journal Article
Carter, D. R.; Murray , J.; Cheung, B. B.; Gamble, L.; Koach, J.; Tsang, J.; Sutton, S.; Kalla, H.; Syed, S.; Gifford, A. J. et al.; Issaeva, N.; Biktasova, A.; Atmadibrata, B.; Sun, Y.; Sokolowski, N.; Ling, D.; Kim, P. Y.; Webber, H.; Clark, A.; Ruhle, M.; Liu, B.; Oberthuer, A.; Fischer, M.; Byrne, J.; Saletta, F.; Thwe, L. M.; Purmal, A.; Haderski, G.; Burkhart, C.; Speleman, F.; De Preter, K.; Beckers, A.; Ziegler, D. S.; Liu, T.; Gurova, K.; Gudkov, A. V.; Norris, M. D.; Haber, M.; Marshall, G. M.: Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma. Science Translational Medicine 7 (312), 312ra176 (2015)
Journal Article
Fey, D.; Halasz, M.; Dreidax, D.; Kennedy, S. P.; Hastings, J. F.; Rauch, N.; Munoz, A. G.; Pilkington, R.; Fischer, M.; Westermann, F. et al.; Kolch, W.; Kholodenko, B. N.; Croucher, D. R.: Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients. Science Signaling 8 (408), ra130 (2015)
Journal Article
Knuever, J.; Willenborg, S.; Ding, X.; Akyuez, M. D.; Partridge, L.; Niessen, C. M.; Brüning, J. C.; Eming, S.: Myeloid cell-restricted insulin/IGF-1 receptor deficiency protects against skin inflammation. Journal of Immunology 195 (11), pp. 5296 - 5308 (2015)
Journal Article
Oster, H.; Brüning, J. C.; Lehnert, H.: Transregionaler Sonderforschungsbereich 134: "Ingestive Behaviour: Homeostasis & Reward". Neuroforum 21 (2), pp. 74 - 77 (2015)
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Peters, F.; Vorhagen, S.; Brodesser, S.; Jakobshagen, K.; Brüning, J. C.; Niessen, C. M.; Krönke, M.: Ceramide synthase 4 regulates stem cell homeostasis and hair follicle cycling. Journal of Investigative Dermatology 135 (6), pp. 1501 - 1509 (2015)
Journal Article
Ruud, J.; Brüning, J. C.: Metabolism: Light on leptin link to lipolysis. Nature 527 (7576), pp. 43 - 44 (2015)
Journal Article
Schönberger, A. R.; Hagelweide, K.; Pelzer, E. A.; Fink, G. R.; Schubotz, R. I.: Motor loop dysfunction causes impaired cognitive sequencing in patients suffering from Parkinson's diseas. Neuropsychologia 77, 5729, pp. 409 - 420 (2015)
Journal Article
Sevgi, M.; Rigoux, L.; Kühn, A. B.; Mauer, J.; Schilbach, L.; Heß, M. E.; Gründler, T. O. J.; Ullsperger, M.; Stephan, K. E.; Brüning, J. C. et al.; Tittgemeyer, M.: An obesity-predisposing variant of the FTO gene regulates D2R-dependent reward learning. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 35 (36), pp. 12584 - 12592 (2015)
Journal Article
Steculorum, S. M.; Paeger, L.; Bremser, S.; Evers, N.; Hinze, Y.; Idzko, M.; Kloppenburg, P.; Brüning, J. C.: Hypothalamic UDP increases in obesity and promotes feeding via P2Y6-dependent activation of AgRP neurons. Cell 162 (6), pp. 1404 - 1417 (2015)
Journal Article
Timper, K.; Seelig, E.; Tsakiris, D. A.; Donath, M. Y.: Safety, pharmacokinetics, and preliminary efficacy of a specific anti-IL-1alpha therapeutic antibody (MABp1) in patients with type 2 diabetes mellitus. Journal of Diabetes and Its Complications 29 (7), pp. 955 - 960 (2015)
Journal Article
Volz, L. J.; Sarfeld, A.-S.; Diekhoff, S.; Rehme, A. K.; Pool, E.-M.; Eickhoff, S. B.; Fink, G. R.; Grefkes, C.: Motor cortex excitability and connectivity in chronic stroke: a multimodal model of functional reorganization. Brain Structure and Function 220 (2), pp. 1093 - 1107 (2015)
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