Publications of Philipp Hammerschmidt

Hammerschmidt, P.; Steculorum, S. M.; Bandet, C. L.; Del Rio-Martin, A.; Steuernagel, L.; Kohlhaas, V.; Feldmann, M.; Varela, L.; Majcher, A.; Quatorze Correia, M. et al.; Klar, R. F.U.; Bauder, C. A.; Kaya, E.; Porniece, M.; Biglari, N.; Sieben, A.; Horvath, T. L.; Hornemann, T.; Brodesser, S.; Brüning, J. C.: CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice. Nature Communications 14 (1), 7824 (2023)

Hammerschmidt, P.; Brüning, J. C.: Contribution of specific ceramides to obesity-associated metabolic diseases. Cellular and Molecular Life Sciences 79 (8), 395 (2022)

Aravamudhan, S.; Türk, C.; Bock, T.; Keufgens, L.; Nolte, H.; Lang, F.; Krishnan, R. K.; König, T.; Hammerschmidt, P.; Schindler, N. et al.; Brodesser, S.; Rozsivalova, D. H.; Rugarli, E. I.; Trifunovic, A.; Brüning, J. C.; Langer, T.; Braun, T.; Krueger, M.: Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. Journal of Molecular and Cellular Cardiology (London) 154, pp. 41 - 49 (2021)

Turpin-Nolan, S. M.; Hammerschmidt, P.; Chen, W.; Jais, A.; Timper, K.; Awazawa, M.; Brodesser, S.; Brüning, J. C.: CerS1-derived C18:0 ceramide in skeletal muscle promotes obesity-induced insulin resistance. Cell Reports 26 (1), pp. 1 - 10.e7 (2019)

Schmidt, E.; Dhaouadi, I.; Gaziano, I.; Oliverio, M.; Klemm, P.; Awazawa, M.; Mitterer, G.; Fernandez-Rebollo, E.; Pradas-Juni, M.; Wagner, W. et al.; Hammerschmidt, P.; Loureiro, R.; Kiefer, C.; Hansmeier, N. R.; Frommolt, P.; Zentis, P.; Orom, U. A.; Heeren, J.; Blüher, M.; Bilban, M.; Kornfeld, J.-W.: LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat. Nature Communications 9, 3622 (2018)

Steculorum, S. M.; Ruud, J.; Karakasilioti, I.; Backes, H.; Engström Ruud, L.; Timper, K.; Heß, M. E.; Tsaousidou, E.; Mauer, J.; Vogt, M. C. et al.; Paeger, L.; Bremser, S.; Klein, A. C.; Morgan, D. A.; Frommolt, P.; Brinkkötter, P. T.; Hammerschmidt, P.; Benzing, T.; Rahmouni, K.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue. Cell 165 (1), pp. 125 - 138 (2016)

Turpin, S. M.; Nicholls, H. T.; Willmes, D. M.; Mourier, A.; Brodesser, S.; Wunderlich, C. M.; Mauer, J.; Xu, E.; Hammerschmidt, P.; Brönneke, H. S. et al.; Trifunovic, A.; LoSasso, G.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Krönke, M.; Brüning, J. C.: Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metabolism 20 (4), pp. 678 - 686 (2014)