Publications of Motoharu Awazawa

Matsushita, M.; Awazawa, M.; Kobayashi, N.; Ikushima, Y. M.; Soeda, K.; Tamura-Nakano, M.; Muratani, M.; Kobayashi, K.; Bluher, M.; Brüning, J. C. et al.; Ueki, K.: An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance. Cell Chemical Biology 29 (4), pp. 680 - 689.e6 (2022)

Pradas-Juni, M.; Hansmeier, N. R.; Link, J. C.; Schmidt, E.; Larsen , B. D.; Klemm, P.; Meola, N.; Topel, H.; Loureiro, R.; Dhaouadi, I. et al.; Kiefer, C. A.; Schwarzer, R.; Khani, S.; Oliverio, M.; Awazawa, M.; Frommolt, P.; Heeren, J.; Scheja, L.; Heine, M.; Dieterich, C.; Büning, H.; Yang, L.; Cao, H.; De Jesus, D. F.; Kulkarni, R. N.; Zevnik, B.; Tröder, S. E.; Knippschild, U.; Edwards, P. A.; Lee, R. G.; Yamamoto, M.; Ulitsky, I.; Fernandez-Rebollo, E.; Vallim, T. Q. d. A.; Kornfeld, J.-W.: A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Nature Communications 11 (1), 644 (2020)

Hammerschmidt, P.; Ostkotte, D.; Nolte, H.; Gerl, M. J.; Jais, A.; Brunner, H. L.; Sprenger, H.-G.; Awazawa, M.; Nicholls, H. T.; Turpin-Nolan, S. M. et al.; Langer, T.; Krüger, M.; Brügger, B.; Brüning, J. C.: CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity. Cell 177 (6), pp. 1536 - 1552.e23 (2019)

Turpin-Nolan, S. M.; Hammerschmidt, P.; Chen, W.; Jais, A.; Timper, K.; Awazawa, M.; Brodesser, S.; Brüning, J. C.: CerS1-derived C18:0 ceramide in skeletal muscle promotes obesity-induced insulin resistance. Cell Reports 26 (1), pp. 1 - 10.e7 (2019)

Brandt, C.; Nolte, H.; Henschke, S.; Ruud, L. E.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Günther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krüger, M.; Brüning, J. C.: Food perception primes hepatic ER homeostasis via melanocortin-dependent control of mTOR activation. Cell 175 (5), pp. 1321 - 1335.e.20 (2018)

Schmidt, E.; Dhaouadi, I.; Gaziano, I.; Oliverio, M.; Klemm, P.; Awazawa, M.; Mitterer, G.; Fernandez-Rebollo, E.; Pradas-Juni, M.; Wagner, W. et al.; Hammerschmidt, P.; Loureiro, R.; Kiefer, C.; Hansmeier, N. R.; Frommolt, P.; Zentis, P.; Orom, U. A.; Heeren, J.; Blüher, M.; Bilban, M.; Kornfeld, J.-W.: LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat. Nature Communications 9, 3622 (2018)

Awazawa, M.; Gabel, P.; Tsaousidou, E.; Nolte, H.; Krüger, M.; Schmitz, J.; Ackermann, J. P.; Brandt, C.; Altmueller, J.; Motameny, S. et al.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Brüning, J. C.: A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nature Medicine 23 (12), pp. 1466 - 1473 (2017)

Schmitz, J.; Evers, N.; Awazawa, M.; Nicholls, H. T.; Brönneke, H. S.; Dietrich, A.; Mauer, J.; Blüher, M.; Brüning, J. C.: Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss. Molecular Metabolism 5 (5), pp. 328 - 339 (2016)

Vogt, M. C.; Paeger, L.; Hess, S.; Steculorum, S. M.; Awazawa, M.; Hampel, B.; Neupert, S.; Nicholls, H. T.; Mauer, J.; Hausen, A. C. et al.; Predel, R.; Kloppenburg, P.; Horvath, T. L.; Brüning, J. C.: Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding. Cell 156 (3), pp. 495 - 509 (2014)