Publications

Borgmann, D.; Fenselau, H.: Vagal pathways for systemic regulation of glucose metabolism. Seminars in Cell & Developmental Biology 156, pp. 244 - 252 (2024)

Ding, C.; Yang, D.; Feldmeyer, D.: Adenosinergic Modulation of Layer 6 Microcircuitry in the Medial Prefrontal Cortex Is Specific to Presynaptic Cell Type. Journal of Neuroscience 44 (15), e1606232023 (2024)

Dodt, S.; Widdershooven, N. V.; Dreisow, M.-L.; Weiher, L.; Steuernagel, L.; Wunderlich, F. T.; Brüning, J. C.; Fenselau, H.: NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation. Nature Communications 15 (1), 5439 (2024)

Engström Ruud, L.; Font-Gironès, F.; Zajdel, J.; Kern, L.; Teixidor-Deulofeu, J.; Manneras-Holm, L.; Carreras, A.; Becattini, B.; Björefeldt, A.; Hanse, E. et al.; Fenselau, H.; Solinas, G.; Brüning, J. C.; Wunderlich, F. T.; Bäckhed, F.; Ruud, J.: Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Reports 43 (4), 113960 (2024)

Sotelo-Hitschfeld, T.; Minère, M.; Klemm, P.; Borgmann, D.; Wnuk-Lipinski, D.; Jais, A.; Jia, X.; Corneliussen, S.; Kloppenburg, P.; Fenselau, H. et al.; Brüning, J. C.: GABAergic disinhibition from the BNST to PNOCARC neurons promotes HFD-induced hyperphagia. Cell Reports 43 (6), 114343 (2024)

Vossen, C.; Schmidt, P.; Wunderlich, C. M.; Mittenbühler, M. J.; Tapken, C.; Wienand, P.; Mirabella, P. N.; Cabot, L.; Schumacher, A.-L.; Folz-Donahue, K. et al.; Kukat, C.; Voigt, I.; Brüning, J. C.; Fenselau, H.; Wunderlich, F. T.: An approach to intersectionally target mature enteroendocrine cells in the small intestine of mice. Cells 13 (1), 102 (2024)

Brüning, J. C.; Fenselau, H.: Integrative neurocircuits that control metabolism and food intake. Science 381 (6665), eabl7398 (2023)

Cabot, L.; Erlenbeck-Dinkelmann, J.; Fenselau, H.: Neural gut-to-brain communication for postprandial control of satiation and glucose metabolism. Journal of Endocrinology 258 (3), e220320 (2023)

Grzelka, K.; Wilhelms, H.; Dodt, S.; Dreisow, M.-L.; Madara, J. C.; Walker, S. J.; Wu, C.; Wang, D.; Klowell, B. B.; Fenselau, H.: A synaptic amplifier of hunger for regaining body weight in the hypothalamus. Cell Metabolism 35 (5), pp. 770 - 785.e5 (2023)

Mirabella, P. N.; Fenselau, H.: Advanced neurobiological tools to interrogate metabolism. Nature Reviews Endocrinology 19 (11), pp. 639 - 654 (2023)

Steuernagel, L.; Lam, B. Y. H.; Klemm, P.; Dowsett, G. K. C.; Bauder, C. A.; Tadross, J. A.; Sotelo-Hitschfeld, T.; Del Rio-Martin, A.; Chen, W.; De Solis, A. J. et al.; Fenselau, H.; Davidsen, P.; Cimino, I.; Kohnke, S. N.; Rimmington, D.; Coll, A. P.; Beyer, A.; Yeo, G. S. H.; Brüning, J. C.: HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus. Nature Metabolism 4 (10), pp. 1402 - 1419 (2022)

Biglari, N.; Gaziano, I.; Schumacher, J.; Radermacher, J.; Paeger, L.; Klemm, P.; Chen, W.; Corneliussen, S.; Wunderlich, C. M.; Sué, M. et al.; Vollmar, S.; Klöckener, T.; Sotelo-Hirschfeld, T.; Abbasloo, A.; Edenhofer, F.; Reimann, F.; Gribble, F. M.; Fenselau, H.; Kloppenburg, P.; Wunderlich, F. T.; Brüning, J. C.: Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nature Neuroscience 24 (7), pp. 913 - 929+ (2021)

Borgmann, D.; Ciglieri, E.; Biglari, N.; Brandt, C.; Cremer, A. L.; Backes, H.; Tittgemeyer, M.; Wunderlich, F. T.; Brüning, J. C.; Fenselau, H.: Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metabolism 33 (7), pp. 1466 - 1482.e7 (2021)

Borgmann, D.; Rigoux, L.; Kuzmanovic, B.; Thanarajah, S. E.; Münte, T. F.; Fenselau, H.; Tittgemeyer, M.: Technical Note: Modulation of fMRI brainstem responses by transcutaneous vagus nerve stimulation. NeuroImage 244, 118566 (2021)

Bozadjieva-Kramer, N.; Ross, R. A.; Johnson, D. Q.; Fenselau, H.; Haggerty, D. L.; Atwood, B.; Lowell, B.; Flak, J. N.: The role of mediobasal hypothalamic PACAP in the control of body weight and metabolism. Endocrinology 162 (4), bqab012 (2021)

Jais, A.; Paeger, L.; Sotelo-Hitschfeld, T.; Bremser, S.; Prinzensteiner, M.; Klemm, P.; Mykytiuk, V.; Widdershooven, P. J.M.; Vesting, A. J.; Grzelka, K. et al.; Minère, M.; Cremer, A. L.; Xu, J.; Korotkova, T.; Lowell, B. B.; Zeilhofer, H. U.; Fenselau, H.; Backes, H.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding. Neuron 106 (6), pp. 1009 - 1025.e10 (2020)

Reinoß, P.; Ciglieri, E.; Minére, M.; Bremser, S.; Klein, A.; Löhr, H.; Fuller, P. M.; Büschges, A.; Kloppenburg, P.; Fenselau, H. et al.; Hammerschmidt, M.: Hypothalamic Pomc neurons innervate the spinal cord and modulate the excitability of premotor circuits. Current Biology 30 (23), pp. 4579 - 4593.e7 (2020)

Ruud, L. E.; Pereira, M. M.; de Solis, A.; Fenselau, H.; Brüning, J. C.: NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons. Nature Communications 11 (1), 442 (2020)

Brandt, C.; Nolte, H.; Henschke, S.; Ruud, L. E.; Awazawa, M.; Morgan, D. A.; Gabel, P.; Sprenger, H.-G.; Hess, M. E.; Günther, S. et al.; Langer, T.; Rahmouni, K.; Fenselau, H.; Krüger, M.; Brüning, J. C.: Food perception primes hepatic ER homeostasis via melanocortin-dependent control of mTOR activation. Cell 175 (5), pp. 1321 - 1335.e.20 (2018)

Todd, W. D.; Fenselau, H.; Wang, J. L.; Zhang, R.; Machado, N. L.; Venner, A.; Broadhurst, R. Y.; Kaur, S.; Lynagh, T.; Olson, D. P. et al.; Lowell, B. B.; Fuller, P. M.; Saper, C. B.: A hypothalamic circuit for the circadian control of aggression. Nature Neuroscience 21 (5), pp. 717 - 724 (2018)