Publications

Cabot, L.; Fenselau, H.: Raptin, a novel brain hormone links sleep health to body weight gain. Cell Research 35, pp. 231 - 232 (2025)

Bethea, M.; Cook, T.; Mommandi, M.; McClennan, A.; Martin, A.; Hendrix, J. J.; Hutch, C. R.; Lewis, A.; Seeley, R. J.; Fenselau, H. et al.; da Silva Teixeria, S.; Sandoval, D. A.: Weight loss reverses obesity-associated impairments in acute gastrointestinal stretch-induced suppression of food intake and glucose homeostasis. Molecular Metabolism 102, 102260, p. 102260 (2025)

Johansen, V. B. I.; Petersen, J.; Lund, J.; Mathiesen, C. V.; Fenselau, H.; Clemmensen, C.: Brain control of energy homeostasis: Implications for anti-obesity pharmacotherapy. Cell 188, pp. 4178 - 4212 (2025)

Minère, M.; Wilhelms, H.; Kuzmanovic, B.; Lundh, S.; Fusca, D.; Claßen, A.; Shtiglitz, S.; Prilutski, Y.; Talpir, I.; Tian, L. et al.; Kieffer, B.; Davis, J.; Kloppenburg, P.; Tittgemeyer, M.; Livneh, Y.; Fenselau, H.: Thalamic opioids from POMC satiety neurons switch on sugar appetite. Science 387, pp. 750 - 758 (2025)

Sakthivelu, V.; Schmitt, A.; Odenthal, F.; Ndoci, K.; Touet, M.; Shaib, A. H.; Chihab, A.; Wani, G. A.; Nieper, P.; Hartmann, G. G. et al.; Pintelon, I.; Kisis, I.; Boecker, M.; Eckert, N. M.; Iannicelli Caiaffa, M.; Ibruli, O.; Weber, J.; Maresch, R.; Bebber, C. M.; Chitsaz, A.; Lütz, A.; Kim Alves Carpinteiro, M.; Morris, K. M.; Franchino, C. A.; Benz, J.; Pérez-Revuelta, L.; Soriano-Campos, J. A.; Huetzen, M. A.; Goergens, J.; Jevtic, M.; Jahn-Kelleter, H. M.; Zempel, H.; Placzek, A.; Hennrich, A. A.; Conzelmann, K.-K.; Tumbrink, H. L.; Hunold, P.; Isensee, J.; Werr, L.; Gaedke, F.; Schauss, A.; Minère, M.; Müller, M.; Fenselau, H.; Liu, Y.; Heimsoeth, A.; Gülcüler Balta, G. S.; Walczak, H.; Frezza, C.; Jachimowicz, R. D.; George, J.; Schmiel, M.; Brägelmann, J.; Hucho, T.; von Karstedt, S.; Peifer, M.; Annibaldi, A.; Hänsel-Hertsch, R.; Persigehl, T.; Grüll, H.; Sos, M. L.; Reifenberger, G.; Fischer, M.; Adriaensen, D.; Büttner, R.; Sage, J.; Brouns, I.; Rad, R.; Thomas, R. K.; Anstötz, M.; Rizzoli, S. O.; Bergami, M.; Motori, E.; Reinhardt, H. C.; Beleggia, F.: Functional synapses between neurons and small cell lung cancer. Nature 646, pp. 1243 - 1253 (2025)

Sakthivelu, V.; Schmitt, A.; Odenthal, F.; Ndoci, K.; Touet, M.; Shaib, A. H.; Chihab, A.; Wani, G. A.; Nieper, P.; Hartmann, G. G. et al.; Pintelon, I.; Kisis, I.; Boecker, M.; Eckert, N. M.; Iannicelli Caiaffa, M.; Ibruli, O.; Weber, J.; Maresch, R.; Bebber, C. M.; Chitsaz, A.; Lütz, A.; Kim Alves Carpinteiro, M.; Morris, K. M.; Franchino, C. A.; Benz, J.; Pérez-Revuelta, L.; Soriano-Campos, J. A.; Huetzen, M. A.; Goergens, J.; Jevtic, M.; Jahn-Kelleter, H. M.; Zempel, H.; Placzek, A.; Hennrich, A. A.; Conzelmann, K.-K.; Tumbrink, H. L.; Hunold, P.; Isensee, J.; Werr, L.; Gaedke, F.; Schauss, A.; Minère, M.; Müller, M.; Fenselau, H.; Liu, Y.; Heimsoeth, A.; Gülcüler Balta, G. S.; Walczak, H.; Frezza, C.; Jachimowicz, R. D.; George, J.; Schmiel, M.; Brägelmann, J.; Hucho, T.; von Karstedt, S.; Peifer, M.; Annibaldi, A.; Hänsel-Hertsch, R.; Persigehl, T.; Grüll, H.; Sos, M. L.; Reifenberger, G.; Fischer, M.; Adriaensen, D.; Büttner, R.; Sage, J.; Brouns, I.; Rad, R.; Thomas, R. K.; Anstötz, M.; Rizzoli, S. O.; Bergami, M.; Motori, E.; Reinhardt, H. C.; Beleggia, F.: Publisher Correction: Functional synapses between neurons and small cell lung cancer. Nature 646, p. E17 - E17 (2025)

Borgmann, D.; Fenselau, H.: Vagal pathways for systemic regulation of glucose metabolism. Seminars in Cell & Developmental Biology 156, pp. 244 - 252 (2024)

Ding, C.; Yang, D.; Feldmeyer, D.: Adenosinergic Modulation of Layer 6 Microcircuitry in the Medial Prefrontal Cortex Is Specific to Presynaptic Cell Type. Journal of Neuroscience 44 (15), e1606232023 (2024)

Dodt, S.; Widdershooven, N. V.; Dreisow, M.-L.; Weiher, L.; Steuernagel, L.; Wunderlich, F. T.; Brüning, J. C.; Fenselau, H.: NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation. Nature Communications 15 (1), 5439 (2024)

Engström Ruud, L.; Font-Gironès, F.; Zajdel, J.; Kern, L.; Teixidor-Deulofeu, J.; Manneras-Holm, L.; Carreras, A.; Becattini, B.; Björefeldt, A.; Hanse, E. et al.; Fenselau, H.; Solinas, G.; Brüning, J. C.; Wunderlich, F. T.; Bäckhed, F.; Ruud, J.: Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Reports 43 (4), 113960 (2024)

Metz, M.; Fenselau, H.: The role of the hypothalamus in the control of the eating behavior. Gynäkologische Endokrinologie 22 (4), pp. 253 - 258 (2024)

Sotelo-Hitschfeld, T.; Minère, M.; Klemm, P.; Borgmann, D.; Wnuk-Lipinski, D.; Jais, A.; Jia, X.; Corneliussen, S.; Kloppenburg, P.; Fenselau, H. et al.; Brüning, J. C.: GABAergic disinhibition from the BNST to PNOCARC neurons promotes HFD-induced hyperphagia. Cell Reports 43 (6), 114343 (2024)

Vossen, C.; Schmidt, P.; Wunderlich, C. M.; Mittenbühler, M. J.; Tapken, C.; Wienand, P.; Mirabella, P. N.; Cabot, L.; Schumacher, A.-L.; Folz-Donahue, K. et al.; Kukat, C.; Voigt, I.; Brüning, J. C.; Fenselau, H.; Wunderlich, F. T.: An approach to intersectionally target mature enteroendocrine cells in the small intestine of mice. Cells 13 (1), 102 (2024)

Brüning, J. C.; Fenselau, H.: Integrative neurocircuits that control metabolism and food intake. Science 381 (6665), eabl7398 (2023)

Cabot, L.; Erlenbeck-Dinkelmann, J.; Fenselau, H.: Neural gut-to-brain communication for postprandial control of satiation and glucose metabolism. Journal of Endocrinology 258 (3), e220320 (2023)

Grzelka, K.; Wilhelms, H.; Dodt, S.; Dreisow, M.-L.; Madara, J. C.; Walker, S. J.; Wu, C.; Wang, D.; Klowell, B. B.; Fenselau, H.: A synaptic amplifier of hunger for regaining body weight in the hypothalamus. Cell Metabolism 35 (5), pp. 770 - 785.e5 (2023)

Mirabella, P. N.; Fenselau, H.: Advanced neurobiological tools to interrogate metabolism. Nature Reviews Endocrinology 19 (11), pp. 639 - 654 (2023)

Steuernagel, L.; Lam, B. Y. H.; Klemm, P.; Dowsett, G. K. C.; Bauder, C. A.; Tadross, J. A.; Sotelo-Hitschfeld, T.; Del Rio-Martin, A.; Chen, W.; De Solis, A. J. et al.; Fenselau, H.; Davidsen, P.; Cimino, I.; Kohnke, S. N.; Rimmington, D.; Coll, A. P.; Beyer, A.; Yeo, G. S. H.; Brüning, J. C.: HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus. Nature Metabolism 4 (10), pp. 1402 - 1419 (2022)

Biglari, N.; Gaziano, I.; Schumacher, J.; Radermacher, J.; Paeger, L.; Klemm, P.; Chen, W.; Corneliussen, S.; Wunderlich, C. M.; Sué, M. et al.; Vollmar, S.; Klöckener, T.; Sotelo-Hirschfeld, T.; Abbasloo, A.; Edenhofer, F.; Reimann, F.; Gribble, F. M.; Fenselau, H.; Kloppenburg, P.; Wunderlich, F. T.; Brüning, J. C.: Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nature Neuroscience 24 (7), pp. 913 - 929+ (2021)

Borgmann, D.; Ciglieri, E.; Biglari, N.; Brandt, C.; Cremer, A. L.; Backes, H.; Tittgemeyer, M.; Wunderlich, F. T.; Brüning, J. C.; Fenselau, H.: Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metabolism 33 (7), pp. 1466 - 1482.e7 (2021)