Publications of Katharina Timper

Ellingsgaard, H.; Seelig, E.; Timper, K.; Coslovsky, M.; Soederlund, L.; Lyngbaek, M. P.; Albrechtsen, N. J. W.; Schmidt-Trucksass, A.; Hanssen, H.; Frey, W. O. et al.; Karstoft, K.; Pedersen, B. K.; Boni-Schnetzler, M.; Donath, M. Y.: GLP-1 secretion is regulated by IL-6 signalling: a randomised, placebo-controlled study. Diabetologia 63 (2), pp. 362 - 373 (2020)

Timper, K.; Del Rio-Martin, A.; Cremer, A. L.; Bremser, S.; Alber, J.; Giavalisco, P.; Varela, L.; Heilinger, C.; Nolte, H.; Trifunovic, A. et al.; Horvath, T. L.; Kloppenburg, P.; Backes, H.; Brüning, J. C.: GLP-1 receptor signaling in astrocytes regulates fatty acid oxidation, mitochondrial integrity, and function. Cell Metabolism 31 (6), pp. 1189 - 1205.e13 (2020)

Turpin-Nolan, S. M.; Hammerschmidt, P.; Chen, W.; Jais, A.; Timper, K.; Awazawa, M.; Brodesser, S.; Brüning, J. C.: CerS1-derived C18:0 ceramide in skeletal muscle promotes obesity-induced insulin resistance. Cell Reports 26 (1), pp. 1 - 10.e7 (2019)

Timper, K.; Paeger, L.; Sanchez-Lasheras, C.; Varela, L.; Jais, A.; Nolte, H.; Vogt, M. C.; Hausen, A. C.; Heilinger, C.; Evers, N. et al.; Pospisilik, J. A.; Penninger, J. M.; Taylor, E. B.; Horvath, T. L.; Kloppenburg, P.; Brüning, J. C.: Mild impairment of mitochondrial OXPHOS promotes fatty acid utilization in POMC neurons and improves glucose homeostasis in obesity. Cell Reports 25 (2), pp. 383 - 397 (2018)

Blum, C. A.; Winzeler, B.; Nigro, N.; Schuetz, P.; Biethahn, S.; Kahles, T.; Mueller, C.; Timper, K.; Haaf, K.; Tepperberg, J. et al.; Amort, M.; Huber, A.; Bingisser, R.; Sándor, P. S.; Nedeltchev, K.; Müller, B.; Katan, M.; Christ-Crain, M.: Copeptin for risk stratification in non-traumatic headache in the emergency setting: a prospective multicenter observational cohort study. The Journal of Headache and Pain 18 (1), 21 (2017)

Seelig, E.; Meyer, S.; Timper, K.; Nigro, N.; Bally, M.; Pernicova, I.; Schuetz, P.; Müller, B.; Korbonits, M.; Christ-Crain, M.: Metformin prevents metabolic side effects during systemic glucocorticoid treatment. European Journal of Endocrinology 176 (3), pp. 349 - 358 (2017)

Steculorum, S. M.; Timper, K.; Engström Ruud, L.; Evers, N.; Paeger, L.; Bremser, S.; Kloppenburg, P.; Brüning, J. C.: Inhibition of P2Y6 signaling in AgRP neurons reduces food intake and improves systemic insulin sensitivity in obesity. Cell Reports 18 (7), pp. 1587 - 1597 (2017)

Theurich, S.; Tsaousidou, E.; Hanssen, R.; Lempradl, A. M.; Mauer, J.; Timper, K.; Schilbach, K.; Folz-Donahue, K.; Heilinger, C.; Sexl, V. et al.; Pospisilik, J. A.; Wunderlich, F. T.; Brüning, J. C.: IL-6/Stat3-dependent induction of a distinct, obesity-associated NK cell subpopulation deteriorates energy and glucose homeostasis. Cell Metabolism 26 (1), pp. 171 - 184 (2017)

Timper, K.; Brüning, J. C.: Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity. Disease Models and Mechanisms 10 (6), pp. 679 - 689 (2017)

Timper, K.; Denson, J. L.; Steculorum, S. M.; Heilinger, C.; Engström-Ruud, L.; Wunderlich, C. M.; Rose-John, S.; Wunderlich, F. T.; Brüning, J. C.: IL-6 improves energy and glucose homeostasis in obesity via enhanced central IL-6 trans-signaling. Cell Reports 19 (2), pp. 267 - 280 (2017)

Steculorum, S. M.; Ruud, J.; Karakasilioti, I.; Backes, H.; Engström Ruud, L.; Timper, K.; Heß, M. E.; Tsaousidou, E.; Mauer, J.; Vogt, M. C. et al.; Paeger, L.; Bremser, S.; Klein, A. C.; Morgan, D. A.; Frommolt, P.; Brinkkötter, P. T.; Hammerschmidt, P.; Benzing, T.; Rahmouni, K.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue. Cell 165 (1), pp. 125 - 138 (2016)

Urwyler, S. A.; Timper, K.; Fenske, W.; De Mota, N.; Blanchard, A.; Kühn, F.; Frech, N.; Arici, B.; Rutishauser, J.; Kopp, P. et al.; Stettler, C.; Müller, B.; Katan, M.; Llorens-Cortes, C.; Christ-Crain, M.: Plasma apelin concentrations in patients with polyuria-polydipsia syndrome. Journal of Clinical Endocrinology and Metabolism 101 (5), pp. 1917 - 1923 (2016)

Timper, K.; Seelig, E.; Tsakiris, D. A.; Donath, M. Y.: Safety, pharmacokinetics, and preliminary efficacy of a specific anti-IL-1alpha therapeutic antibody (MABp1) in patients with type 2 diabetes mellitus. Journal of Diabetes and Its Complications 29 (7), pp. 955 - 960 (2015)