Publications of Claudia Maria Wunderlich

Henschke, S.; Nolte, H.; Magoley, J.; Kleele, T.; Brandt, C.; Hausen, A. C.; Wunderlich, C. M.; Bauder, C.; Aschauer, P.; Manley, S. et al.; Langer, T.; Wunderlich, F. T.; Brüning, J. C.: Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science 384 (6694), pp. 438 - 446 (2024)

Vossen, C.; Schmidt, P.; Wunderlich, C. M.; Mittenbühler, M. J.; Tapken, C.; Wienand, P.; Mirabella, P. N.; Cabot, L.; Schumacher, A.-L.; Folz-Donahue, K. et al.; Kukat, C.; Voigt, I.; Brüning, J. C.; Fenselau, H.; Wunderlich, F. T.: An approach to intersectionally target mature enteroendocrine cells in the small intestine of mice. Cells 13 (1), 102 (2024)

Chen, W.; Mehlkop, O.; Scharn, A.; Nolte, H.; Klemm, P.; Henschke, S.; Steuernagel, L.; Sotelo-Hitschfeld, T.; Kaya, E.; Wunderlich, C. M. et al.; Langer, T.; Kononenko, N. L.; Giavalisco, P.; Brüning, J. C.: Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation. Cell Metabolism 35 (5), pp. 786 - 806.e13 (2023)

Biglari, N.; Gaziano, I.; Schumacher, J.; Radermacher, J.; Paeger, L.; Klemm, P.; Chen, W.; Corneliussen, S.; Wunderlich, C. M.; Sué, M. et al.; Vollmar, S.; Klöckener, T.; Sotelo-Hirschfeld, T.; Abbasloo, A.; Edenhofer, F.; Reimann, F.; Gribble, F. M.; Fenselau, H.; Kloppenburg, P.; Wunderlich, F. T.; Brüning, J. C.: Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nature Neuroscience 24 (7), pp. 913 - 929+ (2021)

Riabinska, A.; Lehrmann, D.; Jachimowicz, R. D.; Knittel, G.; Fritz, C.; Schmitt, A.; Geyer, A.; Heneweer, C.; Wittersheim, M.; Frenzel, L. P. et al.; Torgovnick, A.; Wiederstein, J. L.; Wunderlich, C. M.; Ortmann, M.; Paillard, A.; Wößmann, W.; Borkhardt, A.; Burdach, S.; Hansmann, M.-L.; Rosenwald, A.; Perner, S.; Mall, G.; Klapper, W.; Merseburg, A.; Krüger, M.; Grüll, H.; Persigehl, T.; Wunderlich, F. T.; Peifer, M.; Utermöhlen, O.; Büttner, R.; Beleggia, F.; Reinhardt, H. C.: ATM activity in T cells is critical for immune surveillance of lymphoma in vivo. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 34 (3), pp. 771 - 786 (2020)

Kern, L.; Mittenbühler, M.; Vesting, A. J.; Ostermann, A. L.; Wunderlich, C. M.; Wunderlich, F. T.: Obesity-induced TNF alpha and IL-6 signaling: The missing link between obesity and inflammation-driven liver and colorectal cancers. Cancers 11 (1), 24 (2019)

Ostermann, A. L.; Wunderlich, C. M.; Schneiders, L.; Vogt, M. C.; Woeste, M.A.; Belgardt, B. F.; Niessen, C. M.; Martiny, B.; Schauss, A. C.; Frommolt, P. et al.; Nikolaev, A.; Hövelmeyer, N.; Sears, R.C.; Koch, P.J.; Günzel, D.; Brüning, J. C.; Wunderlich, F. T.: Intestinal insulin/IGF1 signalling through FoxO1 regulates epithelial integrity and susceptibility to colon cancer. Nature Metabolism 1 (3), pp. 371 - 389 (2019)

Löhr, H.; Hess, S.; Robalo de Azevedo Aleixo Pereira, M. M.; Reinoß, P.; Leibold, S.; Schenkel, C.; Wunderlich, C. M.; Kloppenburg, P.; Brüning, J. C.; Hammerschmidt, M.: Diet-induced growth is regulated via acquired Leptin resistance and engages a Pomc-somatostatin-growth hormone circuit. Cell Reports 23 (6), pp. 1728 - 1741 (2018)

Mittenbühler, M.; Sprenger, H.-G.; Gruber, S.; Wunderlich, C. M.; Kern, L.; Brüning, J. C.; Wunderlich, F. T.: Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma. Molecular Metabolism 17, pp. 122 - 133 (2018)

Wunderlich, C. M.; Ackermann, J. P.; Ostermann, A. L.; Adams-Quack, P.; Vogt, M. C.; Tran, M.-L.; Nikolajev, A.; Waisman, A.; Garbers, C.; Theurich, S. et al.; Mauer, J.; Hövelmeyer, N.; Wunderlich, F. T.: Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nature Communications 9 (1), 1646 (2018)

Timper, K.; Denson, J. L.; Steculorum, S. M.; Heilinger, C.; Engström-Ruud, L.; Wunderlich, C. M.; Rose-John, S.; Wunderlich, F. T.; Brüning, J. C.: IL-6 improves energy and glucose homeostasis in obesity via enhanced central IL-6 trans-signaling. Cell Reports 19 (2), pp. 267 - 280 (2017)

Koehler, S.; Brähler, S.; Kuczkowski, A.; Binz, J.; Hackl, M. J.; Hagmann, H.; Höhne, M.; Vogt, M. C.; Wunderlich, C. M.; Wunderlich, F. T. et al.; Schweda, F.; Schermer, B.; Benzing, T.; Brinkkoetter, P. T.: Single and transient Ca2+ peaks in podocytes do not induce changes in glomerular filtration and perfusion. Scientific Reports 6, 35400 (2016)

Baris, O. R.; Ederer, S.; Neuhaus , J. F. G.; von Kleist-Retzow, J.-C.; Wunderlich, C.; Pal, M.; Wunderlich, F. T.; Peeva, V.; Zsurka, G.; Kunz , W. S. et al.; Hickethier, T.; Bunck, A. C.; Stöckigt, F.; Schrickel, J. W.; Wiesner , R. J.: Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging. Cell Metabolism 21 (6), pp. 667 - 677 (2015)

Rastetter, R. H.; Blömacher, M.; Drebber, U.; Marko, M.; Behrens, J.; Soiga, R.; Hojeili, S.; Bhattacharya, K.; Wunderlich, C. M.; Wunderlich, F. T. et al.; Odenthal, M.; Ziemann, A.; Eichinger, L.; Clemen, C. S.: Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling. BMC Cancer 15 (1), 638 (2015)

Andree, M.; Seeger, J. M.; Schüll, S.; Coutelle, O.; Wagner-Stippich, D.; Wiegmann, K.; Wunderlich, C. M.; Brinkmann, K.; Broxtermann, P.; Witt, A. et al.; Fritsch, M.; Martinelli, P.; Bielig, H.; Lamkemeyer, T.; Rugarli, E. I.; Kaufmann, T.; Sterner-Kock, A.; Wunderlich, F. T.; Villunger, A.; Martins, L. M.; Krönke, M.; Kufer, T. A.; Utermöhlen, O.; Kashkar, H.: BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO Journal 33 (19), pp. 2171 - 2187 (2014)

Geibel, M.; Badurek, S.; Horn, J. M.; Vatanashevanopakorn, C.; Koudelka, J.; Wunderlich, C. M.; Brönneke, H. S.; Wunderlich, F. T.; Minichiello, L.: Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity. Nature Communications 5, 3427 (2014)

Tsaousidou, E.; Paeger, L.; Belgardt, B. F.; Pal, M.; Wunderlich, C. M.; Brönneke, H. S.; Collienne, U.; Hampel, B.; Wunderlich, F. T.; Schmidt-Supprian, M. et al.; Kloppenburg, P.; Brüning, J. C.: Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance. Cell Reports 9 (4), pp. 1495 - 1506 (2014)

Turpin, S. M.; Nicholls, H. T.; Willmes, D. M.; Mourier, A.; Brodesser, S.; Wunderlich, C. M.; Mauer, J.; Xu, E.; Hammerschmidt, P.; Brönneke, H. S. et al.; Trifunovic, A.; LoSasso, G.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Krönke, M.; Brüning, J. C.: Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metabolism 20 (4), pp. 678 - 686 (2014)

Gruber, S.; Straub, B.; Ackermann, P. J.; Wunderlich, C. M.; Mauer, J.; Seeger, J. M.; Büning, H.; Heukamp, L.; Kashkar, H.; Schirmacher, P. et al.; Brüning, J. C.; Wunderlich, F. T.: Obesity promotes liver carcinogenesis via Mcl-1 stabilization independent of IL-6Rα signaling. Cell Reports 4 (4), pp. 669 - 680 (2013)

Pal, M.; Wunderlich, C. M.; Spohn, G.; Broenneke, H. S.; Schmidt-Supprian, M.; Wunderlich, F. T.: Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice. PLoS ONE 8 (1), e54247 (2013)