Publikationen von Frank Thomas Wunderlich

Schmidleithner, L.; Thabet, Y.; Schönfeld, E.; Köhne, M.; Sommer, D.; Abdullah, Z.; Sadlon, T.; Osei-Sarpong, C.; Subbaramaiah, K.; Copperi, F. et al.; Haendler, K.; Varga, T.; Schanz, O.; Bourry, S.; Bassler, K.; Krebs, W.; Peters, A. E.; Baumgart, A.-K.; Schneeweiss, M.; Klee, K.; Schmidt, S. V.; Nüssing, S.; Sander, J.; Ohkura, N.; Waha, A.; Sparwasser, T.; Wunderlich, F. T.; Förster, I.; Ulas, T.; Weighardt, H.; Sakaguchi, S.; Pfeifer, A.; Blüher, M.; Dannenberg, A. J.; Ferreiros, N.; Muglia, L. J.; Wickenhauser, C.; Barry, S. C.; Schultze, J. L.; Beyer, M.: Enzymatic activity of HPGD in Treg cells suppresses Tconv cells to maintain adipose tissue homeostasis and prevent metabolic dysfunction. Immunity 50 (5), S. 1232 - 1248.e14 (2019)

Dafinger, C.; Rinschen, M. M.; Borgal, L.; Ehrenberg, C.; Basten, S. G.; Franke, M.; Hoehne, M.; Rauh, M.; Goebel, H.; Bloch, W. et al.; Wunderlich, F. T.; Peters, D. J.M.; Tasche, D.; Mishra, T.; Habbig, S.; Dötsch, J.; Müller, R.-U.; Brüning, J. C.; Persigehl, T.; Giles, R. H.; Benzing, T.; Schermer, B.; Liebau, M. C.: Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus. Experimental and Molecular Medicine 50, 75 (2018)

Hahn, M.; Buerckert, J.-P.; Luttenberger, C.A.; Klebow, S.; Hess, M.E.; Al-Maarri, M.; Vogt, M. C.; Reißig, S.; Hallek, M.; Wienecke-Baldacchino, A. et al.; Buch, T.; Muller, C.P.; Pallasch, C.P.; Wunderlich, F. T.; Waisman, A.; Hoevelmeyer, N.: Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-kappa B signaling. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 32 (1), S. 72 - 82 (2018)

Mittenbühler, M.; Sprenger, H.-G.; Gruber, S.; Wunderlich, C. M.; Kern, L.; Brüning, J. C.; Wunderlich, F. T.: Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma. Molecular Metabolism 17, S. 122 - 133 (2018)

Wunderlich, C. M.; Ackermann, J. P.; Ostermann, A. L.; Adams-Quack, P.; Vogt, M. C.; Tran, M.-L.; Nikolajev, A.; Waisman, A.; Garbers, C.; Theurich, S. et al.; Mauer, J.; Hövelmeyer, N.; Wunderlich, F. T.: Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nature Communications 9 (1), 1646 (2018)

Awazawa, M.; Gabel, P.; Tsaousidou, E.; Nolte, H.; Krüger, M.; Schmitz, J.; Ackermann, J. P.; Brandt, C.; Altmueller, J.; Motameny, S. et al.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Brüning, J. C.: A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nature Medicine 23 (12), S. 1466 - 1473 (2017)

Bergmann, J.; Müller, M.; Baumann, N.; Reichert, M.; Heneweer, C.; Bolik, J.; Lücke, K.; Gruber, S.; Carambia, A.; Boretius, S. et al.; Leuschner, I.; Becker, T.; Rabe, B.; Herkel, J.; Wunderlich, F. T.; Mittrücker, H.-W.; Rose-John, S.; Schmidt-Arras, D.: IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice. Hepatology 65 (1), S. 89 - 103 (2017)

Drees, C.; Vahl, J. C.; Bortoluzzi, S.; Heger, K.; Fischer, J. C.; Wunderlich, F. T.; Peschel, C.; Schmidt-Supprian, M.: Roquin paralogs differentially regulate functional NKT cell subsets. Journal of Immunology 198 (7), S. 2747 - 2759 (2017)

Heink, S.; Yogev, N.; Garbers, C.; Herwerth, M.; Aly, L.; Gasperi, C.; Husterer, V.; Croxford, A. L.; Möller-Hackbarth, K.; Bartsch, H. S. et al.; Sotlar, K.; Krebs, S.; Regen, T.; Blum, H.; Hemmer, B.; Misgeld, T.; Wunderlich, F. T.; Hidalgo, J.; Oukka, M.; Rose-John, S.; Schmidt-Supprian, M.; Waisman, A.; Korn, T.: Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T H 17 cells. Nature Immunology 18 (1), S. 74 - 85 (2017)

Knittel, G.; Rehkämper, T.; Korovkina, D.; Liedgens, P.; Fritz, C.; Torgovnick, A.; Al-Baldawi, Y.; Al-Maarri, M.; Cun, Y.; Fedorchenko, O. et al.; Riabinska, A.; Beleggia, F.; Nguyen, P.-H.; Wunderlich, F. T.; Ortmann, M.; Montesinos-Rongen, M.; Tausch, E.; Stilgenbauer, S.; Frenzel, L.; Herling, M.; Herling, C.; Bahlo, J.; Hallek, M.; Peifer, M.; Buettner, R.; Persigehl, T.; Reinhardt, H. C.: Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nature Communications 8 (1), 153 (2017)

Koehler, S.; Brähler, S.; Braun, F.; Hagmann, H.; Rinschen, M. M.; Späth, M. R.; Höhne, M.; Wunderlich, F. T.; Schermer, B.; Benzing, T. et al.; Brinkkoetter, P. T.: Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes. Kidney International: Official Journal of the International Society of Nephrology 91 (6), S. 1510 - 1517 (2017)

Lauterbach, M. A.R.; Wunderlich, F. T.: Macrophage function in obesity-induced inflammation and insulin resistance. Pflügers Archiv: European Journal of Physiology 469 (3-4), S. 385 - 396 (2017)

Reißig, S.; Tang, Y.; Nikolaev, A.; Gerlach, K.; Wolf, C.; Davari, K.; Gallus, C.; Masri, J.; Mufazalov, I. A.; Neurath, M. F. et al.; Wunderlich, F. T.; Schattenberg, J. M.; Galle, P. R.; Weigmann, B.; Waisman, A.; Glasmacher, E.; Hövelmeyer, N.: Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis. Nature Communications 8, 15069 (2017)

Theurich, S.; Tsaousidou, E.; Hanssen, R.; Lempradl, A. M.; Mauer, J.; Timper, K.; Schilbach, K.; Folz-Donahue, K.; Heilinger, C.; Sexl, V. et al.; Pospisilik, J. A.; Wunderlich, F. T.; Brüning, J. C.: IL-6/Stat3-dependent induction of a distinct, obesity-associated NK cell subpopulation deteriorates energy and glucose homeostasis. Cell Metabolism 26 (1), S. 171 - 184 (2017)

Timper, K.; Denson, J. L.; Steculorum, S. M.; Heilinger, C.; Engström-Ruud, L.; Wunderlich, C. M.; Rose-John, S.; Wunderlich, F. T.; Brüning, J. C.: IL-6 improves energy and glucose homeostasis in obesity via enhanced central IL-6 trans-signaling. Cell Reports 19 (2), S. 267 - 280 (2017)

von Loeffelholz, C.; Lieske, S.; Neuschäfer-Rube, F.; Willmes, D. M.; Raschzok, N.; Sauer, I. M.; König, J.; Fromm, M. F.; Horn, P.; Chatzigeorgiou, A. et al.; Pathe-Neuschäfer-Rube, A.; Jordan, J.; Pfeiffer, A. F.H.; Mingrone, G.; Bornstein, S. R.; Ströhle, P.; Harms, C.; Wunderlich, F. T.; Helfand, S. L.; Bernier, M.; de Cabo, R.; Shulman, G. I.; Chavakis, T.; Püschel, G. P.; Birkenfeld, A. L.: The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. Hepatology 66 (2), S. 616 - 630 (2017)

Xu, E.; Pereira, M. M.; Karakasilioti, I.; Theurich, S.; Al-Maari, M.; Rappl, G.; Waisman, A.; Wunderlich, F. T.; Brüning, J. C.: Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance. Nature Communications 8, 14803 (2017)

Klebow, S.; Hahn, M.; Nikoalev, A.; Wunderlich, F. T.; Hövelmeyer, N.; Karbach, S. H.; Waisman, A.: IL-6 signaling in myelomonocytic cells is not crucial for the development of IMQ-induced psoriasis. PLoS One 11 (3), e0151913 (2016)

Knittel, G.; Liedgens, P.; Korovkina, D.; Seeger, J. M.; Al-Baldawi, Y.; Al-Maarri, M.; Fritz, C.; Vlantis, K.; Bezhanova, S.; Scheel, A. H. et al.; Wolf, O.-O.; Reimann, M.; Möller, P.; Lopez, C.; Schlesner, M.; Lohneis, P.; Weber, A. N.R.; Trümper, L.; Staudt, L. M.; Ortmann, M.; Pasparakis, M.; Siebert, R.; Schmitt, C. A.; Klatt, A. R.; Wunderlich, F. T.; Schäfer, S. C.; Persigehl, T.; Montesinos-Rongen, M.; Odenthal, M.; Büttner, R.; Frenzel, L. P.; Kashkar, H.; Reinhard, H. C.: B-cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B-cell lymphoma in mice. Blood 127 (22), S. 2732 - 2741 (2016)

Koehler, S.; Brähler, S.; Kuczkowski, A.; Binz, J.; Hackl, M. J.; Hagmann, H.; Höhne, M.; Vogt, M. C.; Wunderlich, C. M.; Wunderlich, F. T. et al.; Schweda, F.; Schermer, B.; Benzing, T.; Brinkkoetter, P. T.: Single and transient Ca2+ peaks in podocytes do not induce changes in glomerular filtration and perfusion. Scientific Reports 6, 35400 (2016)