Publikationen von Jens Claus Brüning

Hune, T. L.K.; Mamone, S.; Schmidt, A. B.; Mahu, I.; D'Apolito, N.; Wiedermann, D.; Brüning, J. C.; Glöggler, S.: Hyperpolarized multi-organ spectroscopy of liver and brain using 1-C-13-pyruvate enhanced via parahydrogen. Applied Magnetic Resonance (angenommen)

Chen, W.; Mehlkop, O.; Scharn, A.; Nolte, H.; Klemm, P.; Henschke, S.; Steuernagel, L.; Sotelo-Hitschfeld, T.; Kaya, E.; Wunderlich, C. M. et al.; Langer, T.; Kononenko, N. L.; Giavalisco, P.; Brüning, J. C.: Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation. Cell Metabolism 35 (5), S. 786 - 806.e13 (2023)

Edwin Thanarajah, S.; DiFeliceantonio, A.; Albus, K.; Kuzmanovic, B.; Rigoux, L.; Iglesias, S.; Hanßen, R.; Schlamann, M.; Cornely, O. A.; Brüning, J. C. et al.; Tittgemeyer, M.; Small, D. M.: Habitual daily intake of a sweet and fatty snack modulates reward processing in humans. Cell Metabolism 35 (4), S. 571 - 584.e6 (2023)

Griess, K.; Rieck, M.; Müller, N.; Karsai, G.; Hartwig, S.; Pelligra, A.; Hardt, R.; Schlegel, C.; Kuboth, J.; Uhlemeyer, C. et al.; Trenkamp, S.; Jeruschke, K.; Weiss, J.; Peifer-Weiss, L.; Xu, W.; Cames, S.; Yi, X.; Cnop, M.; Beller, M.; Stark, H.; Kondadi, A. K.; Reichert, A. S.; Markgraf, D.; Wammers, M.; Häussinger, D.; Kuss, O.; Lehr, S.; Eizirik, D.; Lickert, H.; Lammert, E.; Roden, M.; Winter, D.; Al-Hasani, H.; Höglinger, D.; Hornemann, T.; Brüning, J. C.; Belgardt, B.-F.: Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis. Nature Cell Biology 25 (1), S. 20 - 29 (2023)

Hanssen, R.; Rigoux, L.; Albus, K.; Kretschmer, A. C.; Thanarajah, S. E.; Chen, W. Y.; Hinze, Y.; Giavalisco, P.; Steculorum, S. M.; Cornely, O. A. et al.; Brüning, J. C.; Tittgemeyer, M.: Circulating uridine dynamically and adaptively regulates food intake in humans. Cell Reports Medicine 4 (1), 100897 (2023)

Hanßen, R.; Rigoux, L.; Kuzmanovic, B.; Iglesias, S.; Kretschmer, A. C.; Schlamann, M.; Albus, K.; Thanarajah, S. E.; Sitnikow, T.; Melzer, C. et al.; Cornely, O. A.; Brüning, J. C.; Tittgemeyer, M.: Liraglutide restores impaired associative learning in individuals with obesity. Nature Metabolism 5 (8), S. 1352 - 1363 (2023)

Parra-Vargas, M.; Bouret, S. G.; Brüning, J. C.; de Moura, E. G.; Garland, T.; Lisboa, P. C.; Ozanne, S. E.; Patti, M.-E.; Plagemann, A.; Speakman, J. R. et al.; Tena-Sempere, M.; Vergely, C.; Zeltser, L. M.; Jiménez-Chillarón, J. C.: The long-lasting shadow of litter size in rodents: litter size is an underreported variable that strongly determines adult physiology. Molecular Metabolism 71, 101707 (2023)

Teo, J. D.; Marian, O. C.; Spiteri, A. G.; Nicholson, M.; Song, H.; Khor, J. X. Y.; McEwen, H. P.; Ge, A.; Sen, M. K.; Piccio, L. et al.; Fletcher, J. L.; King, N. J. C.; Murray, S. S.; Brüning, J. C.; Don, A. S.: Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes. Glia 71 (4), S. 1120 - 1141 (2023)

Gaziano, I.; Corneliussen, S.; Biglari, N.; Neuhaus, R.; Shen, L.; Sotelo-Hitschfeld, T.; Klemm, P.; Steuernagel, L.; de Solis, A.; Chen, W. et al.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: Dopamine-inhibited POMCDrd2+neurons in the ARC acutely regulate feeding and body temperature. JCI Insight 7 (21), e162753 (2022)

Hammerschmidt, P.; Brüning, J. C.: Contribution of specific ceramides to obesity-associated metabolic diseases. Cellular and Molecular Life Sciences 79 (8), 395 (2022)

Hanssen, R.; Thanarajah, S. E.; Tittgemeyer, M.; Brüning, J. C.: Obesity - A Matter of Motivation? Experimental and Clinical Endocrinology & Diabetes 130 (5), S. 290 - 295 (2022)

Hoyer-Allo, K. J. R.; Späth, M. R.; Brodesser, S.; Zhu, Y.; Binz-Lotter, J.; Höhne, M.; Brönneke, H. S.; Bohl, K.; Johnsen, M.; Kubacki, T. et al.; Kiefer, K.; Seufert, L.; Koehler, F. C.; Grundmann, F.; Hackl, M. J.; Schermer, B.; Brüning, J. C.; Benzing, T.; Burst, V.; Müller, R. U.: Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney International 102 (3), S. 560 - 576 (2022)

Jais, A.; Brüning, J. C.: Arcuate nucleus-dependent regulation of metabolism - pathways to obesity and diabetes mellitus. Endocrine Reviews 43 (2), S. 314 - 328 (2022)

Lippert, R. N.; Brüning, J. C.: Maternal metabolic programming of the developing central nervous system – unified pathways to metabolic and psychiatric disorders. Biological Psychiatry 91 (10), S. 898 - 906 (2022)

Matsushita, M.; Awazawa, M.; Kobayashi, N.; Ikushima, Y. M.; Soeda, K.; Tamura-Nakano, M.; Muratani, M.; Kobayashi, K.; Bluher, M.; Brüning, J. C. et al.; Ueki, K.: An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance. Cell Chemical Biology 29 (4), S. 680 - 689.e6 (2022)

Meron, E.; Thaysen, M.; Angeli, S.; Antebi, A.; Barzilai, N.; Baur, J. A.; Bekker-Jensen, S.; Birkisdottir, M.; Bischof, E.; Brüning, J. C. et al.; Brunet, A.; Buchwalter, A.; Cabreiro, F.; Cai, S.; Chen, B. H.; Ermolaeva, M.; Ewald, C. Y.; Ferrucci, L.; Florian, M. C.; Fortney, K.; Freund, A.; Georgievskaya, A.; Gladyshev, V. N.; Glass, D.; Golato, T.; Gorbunova, V.; Hoejimakers, J.; Houtkooper, R. H.; Jager, S.; Jaksch, F.; Janssens, G.; Jensen, M. B.; Kaeberlein, M.; Karsenty, G.; de Keizer, P.; Kennedy, B.; Kirkland, J. L.; Kjaer, M.; Kroemer, G.; Lee, K.-F.; Lemaitre, J.-M.; Liaskos, D.; Longo, V. D.; Lu, Y.-X.; MacArthur, M. R.; Maier, A. B.; Manakanatas, C.; Mitchell, S. J.; Moskalev, A.; Niedernhofer, L.; Ozerov, I.; Partridge, L.; Passegue, E.; Petr, M. A.; Peyer, J.; Radenkovic, D.; Rando, T. A.; Rattan, S.; Riedel, C. G.; Rudolph, L.; Ai, R.; Serrano, M.; Schumacher, B.; Sinclair, D. A.; Smith, R.; Suh, Y.; Taub, P.; Trapp, A.; Trendelenburg, A.-U.; Valenzano, D. R.; Verburgh, K.; Verdin, E.; Vijg, J.; Westendorp, R. G.J.; Zonari, A.; Bakula, D.; Zhavoronkov, A.; Scheibye-Knudsen, M.: Meeting Report: Aging Research and Drug Discovery. Aging 14 (2), S. 530 - 543 (2022)

Ramírez, S.; Haddad-Tóvolli, R.; Radosevic, M.; Toledo, M.; Pané, A.; Alcolea, D.; Ribas, V.; Milà-Guasch, M.; Pozo, M.; Obri, A. et al.; Eyre, E.; Gómez-Valadés, A. G.; Chivite, I.; Van Eeckhout, T.; Zalachoras, I.; Altirriba, J.; Bauder, C.; Imbernón, M.; Garrabou, G.; Garcia-Ruiz, C.; Nogueiras, R.; Soto, D.; Gasull, X.; Sandi, C.; Brüning, J. C.; Fortea, J.; Jiménez, A.; Fernández-Checa, J. C.; Claret, M.: Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metabolism 34 (2), S. 269 - 284.e9 (2022)

Steuernagel, L.; Lam, B. Y. H.; Klemm, P.; Dowsett, G. K. C.; Bauder, C. A.; Tadross, J. A.; Sotelo-Hitschfeld, T.; Del Rio-Martin, A.; Chen, W.; De Solis, A. J. et al.; Fenselau, H.; Davidsen, P.; Cimino, I.; Kohnke, S. N.; Rimmington, D.; Coll, A. P.; Beyer, A.; Yeo, G. S. H.; Brüning, J. C.: HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus. Nature Metabolism 4 (10), S. 1402 - 1419 (2022)

Vesting, A. J.; Jais, A.; Klemm, P.; Steuernagel, L.; Wienand, P.; Fog-Tonnesen, M.; Hvid, H.; Schumacher, A.-L.; Kukat, C.; Nolte, H. et al.; Georgomanolis, T.; Altmüller, J.; Pasparakis, M.; Schmidt, A.; Krüger, M.; Supprian, M. S.; Waisman, A.; Straub, B. K.; Raschzok, N.; Bernier, M.; Birkenfeld, A. L.; Hövelmeyer, N.; Brüning, J. C.; Wunderlich, F. T.: NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Molecular Metabolism 66, 101626 (2022)

Biglari, N.; Gaziano, I.; Schumacher, J.; Radermacher, J.; Paeger, L.; Klemm, P.; Chen, W.; Corneliussen, S.; Wunderlich, C. M.; Sué, M. et al.; Vollmar, S.; Klöckener, T.; Sotelo-Hirschfeld, T.; Abbasloo, A.; Edenhofer, F.; Reimann, F.; Gribble, F. M.; Fenselau, H.; Kloppenburg, P.; Wunderlich, F. T.; Brüning, J. C.: Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nature Neuroscience 24 (7), S. 913 - 929+ (2021)