Publications of Jens Claus Brüning

Journal Article (126)

1.
Journal Article
Jais, A.; Brüning, J. C.: Arcuate nucleus-dependent regulation of metabolism - pathways to obesity and diabetes mellitus. Endocrine Reviews (accepted)
2.
Journal Article
Lippert, R. N.; Brüning, J. C.: Maternal metabolic programming of the developing central nervous system – unified pathways to metabolic and psychiatric disorders. Biological Psychiatry (accepted)
3.
Journal Article
Biglari, N.; Gaziano, I.; Schumacher, J.; Radermacher, J.; Paeger, L.; Klemm, P.; Chen, W.; Corneliussen, S.; Wunderlich, C. M.; Sué, M. et al.; Vollmar, S.; Klöckener, T.; Sotelo-Hirschfeld, T.; Abbasloo, A.; Edenhofer, F.; Reimann, F.; Gribble, F. M.; Fenselau, H.; Kloppenburg, P.; Wunderlich, F. T.; Brüning, J. C.: Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nature Neuroscience 24 (7), pp. 913 - 929+ (2021)
4.
Journal Article
Aravamudhan, S.; Türk, C.; Bock, T.; Keufgens, L.; Nolte, H.; Lang, F.; Krishnan, R. K.; König, T.; Hammerschmidt, P.; Schindler, N. et al.; Brodesser, S.; Rozsivalova, D. H.; Rugarli, E. I.; Trifunovic, A.; Brüning, J. C.; Langer, T.; Braun, T.; Krueger, M.: Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. Journal of Molecular and Cellular Cardiology (London) 154, pp. 41 - 49 (2021)
5.
Journal Article
Borgmann, D.; Ciglieri, E.; Biglari, N.; Brandt, C.; Cremer, A. L.; Backes, H.; Tittgemeyer, M.; Wunderlich, F. T.; Brüning, J. C.; Fenselau, H.: Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metabolism 33 (7), pp. 1466 - 1482.e7 (2021)
6.
Journal Article
Brüning, J. C.; García Cáceres, C.; Heni , M.; Preißl, H.: Insulinwirkung und -resistenz im Gehirn. Diabetes Aktuell 19 (2), pp. 72 - 75 (2021)
7.
Journal Article
Dodd, G. T.; Kim, S. J.; Mequinion, M.; Xirouchaki, C. E.; Brüning, J. C.; Andrews, Z. B.; Tiganis, T.: Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance. Science Advances 7 (9), eabf4100 (2021)
8.
Journal Article
Hanssen, R.; Kretschmer, A. C.; Rigoux, L.; Albus, K.; Thanarajah, S. E.; Sitnikow, T.; Melzer, C.; Cornely, O. A.; Brüning, J. C.; Tittgemeyer, M.: GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Molecular Metabolism 45, 101163 (2021)
9.
Journal Article
Hoyer-Allo, K. J. R.; Späth, M. R.; Hanssen, R.; Johnsen, M.; Brodesser, S.; Kaufmann, K.; Kiefer, K.; Koehler, F. C.; Göbel, H.; Kubacki, T. et al.; Grundmann, F.; Schermer, B.; Brüning, J. C.; Benzing, T.; Burst, V.; Müller, R.-U.: Modulation of endocannabinoids by caloric restriction is conserved in mice but is not required for protection from acute kidney injury. International Journal of Molecular Sciences 22 (11), 5485 (2021)
10.
Journal Article
Kohlhaas, V.; Blakemore, S. J.; Al-Maarri, M.; Nickel, N.; Pal, M.; Roth, A.; Hövelmeyer, N.; Schäfer, S. C.; Knittel, G.; Lohneis, P. et al.; Nikolic, M.; Wiederstein, J. L.; Franitza, M.; Georgomonolis, T.; Reinart, N.; Herling, M.; Herling, C.; Hartmann, E. M.; Rosenwald, A.; Klapper, W.; Büttner, R.; Moia, R.; Rossi, D.; Boldorini, R.; Gaidano, G.; Frenzel, L. P.; Reinhardt, H. C.; Brüning, J. C.; Hallek, M.; Krüger, M.; Peifer, M.; Pallasch, C. P.; Wunderlich, F. T.: Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood 137 (5), pp. 646 - 660 (2021)
11.
Journal Article
Quarta, C.; Claret, M.; Zeltser, L. M.; Williams, K. W.; Yeo, G. S.H.; Tschöp, M. H.; Diano, S.; Brüning, J. C.; Cota, D.: POMC neuronal heterogeneity in energy balance and beyond: an integrated view. Nature Metabolism 3 (3), pp. 299 - 308 (2021)
12.
Journal Article
Welcker, D.; Stein, C.; Feitosa, N. M.; Armistead, J.; Zhang, J.-L.; Lütke, S.; Kleinridders, A.; Brüning, J. C.; Eming, S. A.; Sengle, G. et al.; Niehoff, A.; Bloch, W.; Hammerschmidt, M.: Hemicentin-1 is an essential extracellular matrix component of the dermal–epidermal and myotendinous junctions. Scientific Reports 11, 17926 (2021)
13.
Journal Article
Xiao, X.; Yeghiazaryan, G.; Hess, S.; Klemm, P.; Sieben, A.; Kleinridders, A.; Morgan, D. A.; Wunderlich, F. T.; Rahmouni, K.; Kong, D. et al.; Scammell, T. E.; Lowell, B. B.; Kloppenburg, P.; Brüning, J. C.; Hausen, A. C.: Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nature Communications 12, 5249 (2021)
14.
Journal Article
Chowdhury, S.; Schulz, L.; Palmisano, B.; Singh, P.; Berger, J. M.; Yadav, V. K.; Mera, P.; Ellingsgaard, H.; Hidalgo, J.; Brüning, J. C. et al.; Karsenty, G.: Muscle-derived interleukin 6 increases exercise capacity by signaling in osteoblasts. Journal of Clinical Investigation 130 (6), pp. 2888 - 2902 (2020)
15.
Journal Article
Ding, X.; Willenborg, S.; Bloch, W.; Wickström, S. A.; Wagle, P.; Brodesser, S.; Roers, A.; Jais, A.; Brüning, J. C.; Hall, M. N. et al.; Rüegg, M. A.; Eming, S. A.: Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. Journal of Allergy and Clinical Immunology 145 (1), pp. 283 - 300.e8 (2020)
16.
Journal Article
DiToro, D.; Harbour, S. N.; Brando, J. K.; Benavides, G.; Witte, S.; Laufer, V. A.; Moseley, C.; Singer, J. R.; Frey, B.; Turner, H. et al.; Brüning, J. C.; Darley-Usmar, V.; Gao, M.; Conover, C.; Hatton, R. D.; Frank, S.; Colonna, M.; Weaver, C. T.: Insulin-Like growth factors are key regulators of T helper 17 regulatory T cell balance in autoimmunity. Immunity 52 (4), pp. 650 - 667 (2020)
17.
Journal Article
Fischer, K.; Fenzl, A.; Liu, D.; Dyar, K. A.; Kleinert, M.; Brielmeier, M.; Clemmensen, C.; Fedl, A.; Finan, B.; Gessner, A. et al.; Jastroch, M.; Huang, J.; Keipert, S.; Klingenspor, M.; Brüning, J. C.; Kneilling, M.; Maier, F. C.; Othman, A. E.; Pichler, B. J.; Pramme-Steinwachs, I.; Sachs, S.; Scheideler, A.; Thaiss, W. M.; Uhlenhaut, H.; Ussar, S.; Woods, S. C.; Zorn, J.; Stemmer, K.; Collins, S.; Diaz-Meco, M.; Moscat, J.; Tschöp, M. H.; Müller, T. D.: The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. Nature Communications 11 (1), 2306 (2020)
18.
Journal Article
Jais, A.; Paeger, L.; Sotelo-Hirschfeld, T.; Bremser, S.; Prinzensteiner, M.; Klemm, P.; Mykytiuk, V.; Widdershooven, P. J.M.; Vesting, A. J.; Grzelka, K. et al.; Minère, M.; Cremer, A. L.; Xu, J.; Korotkova, T.; Lowell, . B.; Zeilhofer, H. U.; Backes, H.; Fenselau, H.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding. Neuron 106 (6), pp. 1009 - 1025.e10 (2020)
19.
Journal Article
Jiang, H.; Gallet, S.; Klemm, P.; Scholl, P.; Folz-Donahue, K.; Altmüller, J.; Alber, J.; Heilinger, C.; Kukat, C.; Loyens, A. et al.; Müller-Fielitz, H.; Sundaram, S.; Schwaninger, M.; Prevot, V.; Brüning, J. C.: MCH neurons regulate permeability of the median eminence barrier. Neuron 107 (2), pp. 306 - 319.e9 (2020)
20.
Journal Article
Koch, C.E.; Begemann, K.; Kiehn, J.T.; Griewahn, L.; Mauer, J.; Heß, M. E.; Moser, A.; Schmid, S.M.; Brüning, J. C.; Oster, H.: Circadian regulation of hedonic appetite in mice by clocks in dopaminergic neurons of the VTA. Nature Communications 11 (1), 3071 (2020)
Go to Editor View