Abteilung Brüning

Zeitschriftenartikel (185)

2023
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Hune, T. L.K.; Mamone, S.; Schmidt, A. B.; Mahu, I.; D'Apolito, N.; Wiedermann, D.; Brüning, J. C.; Glöggler, S.: Hyperpolarized multi-organ spectroscopy of liver and brain using 1-C-13-pyruvate enhanced via parahydrogen. Applied Magnetic Resonance 54 (11-12), S. 1283 - 1295 (2023)
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Norberto, S.; Assalin, H. B.; Guadagnini, D.; Tobar, N.; Boer, P. A.; Kang, M.-C.; Saad, M. J. A.; Kim, Y.-B.; Prada, P. O. d.: CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion. Frontiers in Endocrinology 14, 1172835 (2023)
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Oliveira Ferreira, C. K. d.; Campolim, C. M.; Zordao, O. P.; Simabuco, F. M.; Anaruma, C. P.; Pereira, R. M.; Boico, V. F.; Salvino, L. G.; Costa, M. M.; Ruiz, N. Q. et al.; de Moura, L. P.; Saad, M. J. A.; Costa, S. K. P.; Kim, Y.-B.; Prada, P. O. d.: Subchronic exposure to 1,2-naphthoquinone induces adipose tissue inflammation and changes the energy homeostasis of mice, partially due to TNFR1 and TLR4. Toxicology Reports 11, S. 10 - 22 (2023)
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Parra-Vargas, M.; Bouret, S. G.; Brüning, J. C.; de Moura, E. G.; Garland, T.; Lisboa, P. C.; Ozanne, S. E.; Patti, M.-E.; Plagemann, A.; Speakman, J. R. et al.; Tena-Sempere, M.; Vergely, C.; Zeltser, L. M.; Jiménez-Chillarón, J. C.: The long-lasting shadow of litter size in rodents: litter size is an underreported variable that strongly determines adult physiology. Molecular Metabolism 71, 101707 (2023)
2022
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Gaziano, I.; Corneliussen, S.; Biglari, N.; Neuhaus, R.; Shen, L.; Sotelo-Hitschfeld, T.; Klemm, P.; Steuernagel, L.; de Solis, A.; Chen, W. et al.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: Dopamine-inhibited POMCDrd2+neurons in the ARC acutely regulate feeding and body temperature. JCI Insight 7 (21), e162753 (2022)
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Hammerschmidt, P.; Brüning, J. C.: Contribution of specific ceramides to obesity-associated metabolic diseases. Cellular and Molecular Life Sciences 79 (8), 395 (2022)
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Hanssen, R.; Thanarajah, S. E.; Tittgemeyer, M.; Brüning, J. C.: Obesity - A Matter of Motivation? Experimental and Clinical Endocrinology & Diabetes 130 (5), S. 290 - 295 (2022)
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Hoyer-Allo, K. J. R.; Späth, M. R.; Brodesser, S.; Zhu, Y.; Binz-Lotter, J.; Höhne, M.; Brönneke, H. S.; Bohl, K.; Johnsen, M.; Kubacki, T. et al.; Kiefer, K.; Seufert, L.; Koehler, F. C.; Grundmann, F.; Hackl, M. J.; Schermer, B.; Brüning, J. C.; Benzing, T.; Burst, V.; Müller, R. U.: Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney International 102 (3), S. 560 - 576 (2022)
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Jais, A.; Brüning, J. C.: Arcuate nucleus-dependent regulation of metabolism - pathways to obesity and diabetes mellitus. Endocrine Reviews 43 (2), S. 314 - 328 (2022)
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Kasper, L.; Engel, M.; Heinzle, J.; Mueller-Schrader, M.; Graedel, N. N.; Reber, J.; Schmid, T.; Barmet, C.; Wilm, B. J.; Stephan, K. E. et al.; Pruessmann, K. P.: Advances in Spiral fMRI: A High-resolution Study with Single-shot Acquisition. NeuroImage 246, 118738 (2022)
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Lippert, R. N.; Brüning, J. C.: Maternal metabolic programming of the developing central nervous system – unified pathways to metabolic and psychiatric disorders. Biological Psychiatry 91 (10), S. 898 - 906 (2022)
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Matsushita, M.; Awazawa, M.; Kobayashi, N.; Ikushima, Y. M.; Soeda, K.; Tamura-Nakano, M.; Muratani, M.; Kobayashi, K.; Bluher, M.; Brüning, J. C. et al.; Ueki, K.: An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance. Cell Chemical Biology 29 (4), S. 680 - 689.e6 (2022)
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Meron, E.; Thaysen, M.; Angeli, S.; Antebi, A.; Barzilai, N.; Baur, J. A.; Bekker-Jensen, S.; Birkisdottir, M.; Bischof, E.; Brüning, J. C. et al.; Brunet, A.; Buchwalter, A.; Cabreiro, F.; Cai, S.; Chen, B. H.; Ermolaeva, M.; Ewald, C. Y.; Ferrucci, L.; Florian, M. C.; Fortney, K.; Freund, A.; Georgievskaya, A.; Gladyshev, V. N.; Glass, D.; Golato, T.; Gorbunova, V.; Hoejimakers, J.; Houtkooper, R. H.; Jager, S.; Jaksch, F.; Janssens, G.; Jensen, M. B.; Kaeberlein, M.; Karsenty, G.; de Keizer, P.; Kennedy, B.; Kirkland, J. L.; Kjaer, M.; Kroemer, G.; Lee, K.-F.; Lemaitre, J.-M.; Liaskos, D.; Longo, V. D.; Lu, Y.-X.; MacArthur, M. R.; Maier, A. B.; Manakanatas, C.; Mitchell, S. J.; Moskalev, A.; Niedernhofer, L.; Ozerov, I.; Partridge, L.; Passegue, E.; Petr, M. A.; Peyer, J.; Radenkovic, D.; Rando, T. A.; Rattan, S.; Riedel, C. G.; Rudolph, L.; Ai, R.; Serrano, M.; Schumacher, B.; Sinclair, D. A.; Smith, R.; Suh, Y.; Taub, P.; Trapp, A.; Trendelenburg, A.-U.; Valenzano, D. R.; Verburgh, K.; Verdin, E.; Vijg, J.; Westendorp, R. G.J.; Zonari, A.; Bakula, D.; Zhavoronkov, A.; Scheibye-Knudsen, M.: Meeting Report: Aging Research and Drug Discovery. Aging 14 (2), S. 530 - 543 (2022)
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Ramírez, S.; Haddad-Tóvolli, R.; Radosevic, M.; Toledo, M.; Pané, A.; Alcolea, D.; Ribas, V.; Milà-Guasch, M.; Pozo, M.; Obri, A. et al.; Eyre, E.; Gómez-Valadés, A. G.; Chivite, I.; Van Eeckhout, T.; Zalachoras, I.; Altirriba, J.; Bauder, C.; Imbernón, M.; Garrabou, G.; Garcia-Ruiz, C.; Nogueiras, R.; Soto, D.; Gasull, X.; Sandi, C.; Brüning, J. C.; Fortea, J.; Jiménez, A.; Fernández-Checa, J. C.; Claret, M.: Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metabolism 34 (2), S. 269 - 284.e9 (2022)
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Steuernagel, L.; Lam, B. Y. H.; Klemm, P.; Dowsett, G. K. C.; Bauder, C. A.; Tadross, J. A.; Sotelo-Hitschfeld, T.; Del Rio-Martin, A.; Chen, W.; De Solis, A. J. et al.; Fenselau, H.; Davidsen, P.; Cimino, I.; Kohnke, S. N.; Rimmington, D.; Coll, A. P.; Beyer, A.; Yeo, G. S. H.; Brüning, J. C.: HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus. Nature Metabolism 4 (10), S. 1402 - 1419 (2022)
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Vesting, A. J.; Jais, A.; Klemm, P.; Steuernagel, L.; Wienand, P.; Fog-Tonnesen, M.; Hvid, H.; Schumacher, A.-L.; Kukat, C.; Nolte, H. et al.; Georgomanolis, T.; Altmüller, J.; Pasparakis, M.; Schmidt, A.; Krüger, M.; Supprian, M. S.; Waisman, A.; Straub, B. K.; Raschzok, N.; Bernier, M.; Birkenfeld, A. L.; Hövelmeyer, N.; Brüning, J. C.; Wunderlich, F. T.: NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Molecular Metabolism 66, 101626 (2022)
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Werr, L.; Plenker, D.; Dammert, M. A.; Lorenz, C.; Bragelmann, J.; Tumbrink, H. L.; Klein, S.; Schmitt, A.; Buttner, R.; Persigehl, T. et al.; Shokat, K. M.; Wunderlich, F. T.; Schram, A. M.; Peifer, M.; Sos, M. L.; Reinhardt, H. C.; Thomas, R. K.: CD74-NRG1 fusions are oncogenic in vivo and induce therapeutically tractable ERBB2:ERBB3 heterodimerization. Molecular Cancer Therapeutics 21 (5), S. 821 - 830 (2022)
2021
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Biglari, N.; Gaziano, I.; Schumacher, J.; Radermacher, J.; Paeger, L.; Klemm, P.; Chen, W.; Corneliussen, S.; Wunderlich, C. M.; Sué, M. et al.; Vollmar, S.; Klöckener, T.; Sotelo-Hirschfeld, T.; Abbasloo, A.; Edenhofer, F.; Reimann, F.; Gribble, F. M.; Fenselau, H.; Kloppenburg, P.; Wunderlich, F. T.; Brüning, J. C.: Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nature Neuroscience 24 (7), S. 913 - 929+ (2021)
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Aravamudhan, S.; Türk, C.; Bock, T.; Keufgens, L.; Nolte, H.; Lang, F.; Krishnan, R. K.; König, T.; Hammerschmidt, P.; Schindler, N. et al.; Brodesser, S.; Rozsivalova, D. H.; Rugarli, E. I.; Trifunovic, A.; Brüning, J. C.; Langer, T.; Braun, T.; Krueger, M.: Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. Journal of Molecular and Cellular Cardiology (London) 154, S. 41 - 49 (2021)
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Borgmann, D.; Ciglieri, E.; Biglari, N.; Brandt, C.; Cremer, A. L.; Backes, H.; Tittgemeyer, M.; Wunderlich, F. T.; Brüning, J. C.; Fenselau, H.: Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metabolism 33 (7), S. 1466 - 1482.e7 (2021)
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