Publications of Jens Claus Brüning

Wunderlich, C. M.; Delic, D.; Behnke, K.; Meryk, A.; Stroehle, P.; Chaurasia, B.; Al-Quraishy, S.; Wunderlich, F.; Brüning, J. C.; Wunderlich, F. T.: Cutting edge: inhibition of IL-6 trans-signaling protects from Malaria-induced lethality in mice. Journal of Immunology 188 (9), pp. 4141 - 4144 (2012)

Chaudhry, A.; Samstein, R. M.; Treuting, P.; Liang, Y.; Pils, M. C.; Heinrich, J.-M.; Jack, R. S.; Wunderlich, F. T.; Brüning, J. C.; Müller, W. et al.; Rudensky, A. Y.: Interleukin-10 signaling in regulatory T cells Is required for suppression of Th17 cell-mediated inflammation. Immunity 34 (4), pp. 566 - 578 (2011)

Gahete, M. D.; Cordoba-Chacon, J.; Anadumaka, C. V.; Brüning, J. C.; Kahn, C. R.; Luque, R. M.; Kineman, R. D.: Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner. Endocrinology 152 (12), pp. 4825 - 4837 (2011)

Hult, S.; Soylu, R.; Björklund, T.; Belgardt, B. F.; Mauer, J.; Brüning, J. C.; Kirik, D.; Petersen, A.: Mutant Huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits. Cell Metabolism 13 (4), pp. 428 - 439 (2011)

Jordan, S. D.; Krüger, M.; Willmes, D. M.; Redemann, N.; Wunderlich, F. T.; Brönneke, H. S.; Merkwirth, C.; Kashkar, H.; Olkkonen, V. M.; Böttger, T. et al.; Braun, T.; Seibler, J.; Brüning, J. C.: Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nature Cell Biology 13 (4), pp. 434 - 446 (2011)

Klöckener, T.; Hess, S.; Belgardt, B. F.; Paeger, L.; Verhagen, L. A. W.; Husch, A.; Sohn, J.-W.; Hampel, B.; Dhillon, H.; Zigman, J. M. et al.; Lowell, B. B.; Williams, K. W.; Elmquist, J. K.; Horvath, T. L.; Kloppenburg, P.; Brüning, J. C.: High-fat feeding promotes obesity via insulin receptor/PI3k-dependent inhibition of SF-1 VMH neurons. Nature Neuroscience 14 (7), pp. 911 - 918 (2011)

Könner, A. C.; Hess, S.; Tovar, S.; Mesaros, A.; Sanchez-Lasheras, C.; Evers, N.; Verhagen, L. A. W.; Brönneke, H. S.; Kleinridders, A.; Hampel, B. et al.; Kloppenburg, P.; Brüning, J. C.: Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis. Cell Metabolism 13 (6), pp. 720 - 728 (2011)

Li, P.; Cavallero, S.; Gu, Y.; Hughes, J.; Hassan, A. B.; Brüning, J. C.; Pashmforoush, M.; Sucov, H. M.: IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development 138 (9), pp. 1795 - 1805 (2011)

Schubert, M.; Gautam, D.; Surjo, D.; Ueki, K.; Baudler, S.; Schubert, D.; Kondo, T.; Alber, J.; Galldiks, N.; Küstermann, E. et al.; Arndt, S.; Jacobs, A. H.; Krone, W.; Kahn, C. R.; Brüning, J. C.: Role for neuronal insulin resistance in neurodegenerative diseases. Proceedings of the National Academy of Sciences of the United States of America 101 (9), pp. 3100 - 3105 (2004)