Publications of Jens Claus Brüning

Aghdam, S. Y.; Eming, S. E.; Willenborg, S.; Neuhaus, B.; Niessen, C. M.; Partridge, L.; Krieg, T.; Brüning, J. C.: Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochemical and Biophysical Research Communications 421 (2), pp. 197 - 202 (2012)

Blumbach, K.; Niehoff, A.; Belgardt, B. F.; Ehlen, H. W. A.; Schmitz, M.; Hallinger, R.; Schulz, J.-N.; Brüning, J. C.; Krieg, T.; Schubert, M. et al.; Guilberg, D.; Eckes, B.: Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels. Journal of Biological Chemistry 287 (9), pp. 6431 - 6440 (2012)

Könner, A. C.; Brüning, J. C.: Mapping leptin's link to reproduction. Molecular Metabolism 1 (1-2), pp. 5 - 7 (2012)

Könner, A. C.; Brüning, J. C.: Selective insulin and leptin resistance in metabolic disorders. Cell Metabolism 16 (2), pp. 144 - 152 (2012)

Kornfeld, J.-W.; Brüning, J. C.: MyomiRs-133a/b turn off the heat. Nature Cell Biology 14 (12), pp. 1248 - 1249 (2012)

Rother, E.; Belgardt, B. F.; Tsaousidou, E.; Hampel, B.; Waisman, A.; Myers, M. G.; Brüning, J. C.: Acute selective ablation of rat insulin promoter-expressing (RIP HER) neurons defines their orexigenic nature. Proceedings of the National Academy of Sciences of the United States of America 109 (44), pp. 18132 - 18137 (2012)

Tschöp, M. H.; Speakman, J. R.; Arch, J. R. S.; Auwerx, J.; Brüning, J. C.; Chan, L.; Eckel, R. H.; Farese, R. V.; Galgani, J. E.; Hambly, C. et al.; Herman, M. A.; Horvath, T. L.; Kahn, B. B.; Kozma, S. C.; Maratos-Flier, E.; Müller, T. D.; Münzberg, H.; Pfluger, P. T.; Plum, L.; Reitman, M. L.; Rahmouni, K.; Shulman, G. I.; Thomas, G.; Kahn, C. R.; Ravussin, E.: A guide to analysis of mouse energy metabolism. Nature Methods 9 (1), pp. 57 - 63 (2012)

Whitham, M.; Chan, M. H. S.; Pal, M.; Matthews, V. B.; Prelovsek, O.; Lunke, S.; El-Osta, A.; Brönneke, H.; Alber, J.; Brüning, J. C. et al.; Wunderlich, F. T.; Lancaster, G. I.; Febbraio, M. A.: Contraction-induced IL-6 gene transcription in skeletal muscle is regulated by c-jun terminal kinase/Activator protein-1. Journal of Biological Chemistry 287 (14), pp. 10771 - 10779 (2012)

Wunderlich, C. M.; Delic, D.; Behnke, K.; Meryk, A.; Stroehle, P.; Chaurasia, B.; Al-Quraishy, S.; Wunderlich, F.; Brüning, J. C.; Wunderlich, F. T.: Cutting edge: inhibition of IL-6 trans-signaling protects from Malaria-induced lethality in mice. Journal of Immunology 188 (9), pp. 4141 - 4144 (2012)

Chaudhry, A.; Samstein, R. M.; Treuting, P.; Liang, Y.; Pils, M. C.; Heinrich, J.-M.; Jack, R. S.; Wunderlich, F. T.; Brüning, J. C.; Müller, W. et al.; Rudensky, A. Y.: Interleukin-10 signaling in regulatory T cells Is required for suppression of Th17 cell-mediated inflammation. Immunity 34 (4), pp. 566 - 578 (2011)

Gahete, M. D.; Cordoba-Chacon, J.; Anadumaka, C. V.; Brüning, J. C.; Kahn, C. R.; Luque, R. M.; Kineman, R. D.: Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner. Endocrinology 152 (12), pp. 4825 - 4837 (2011)

Hult, S.; Soylu, R.; Björklund, T.; Belgardt, B. F.; Mauer, J.; Brüning, J. C.; Kirik, D.; Petersen, A.: Mutant Huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits. Cell Metabolism 13 (4), pp. 428 - 439 (2011)

Jordan, S. D.; Krüger, M.; Willmes, D. M.; Redemann, N.; Wunderlich, F. T.; Brönneke, H. S.; Merkwirth, C.; Kashkar, H.; Olkkonen, V. M.; Böttger, T. et al.; Braun, T.; Seibler, J.; Brüning, J. C.: Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nature Cell Biology 13 (4), pp. 434 - 446 (2011)

Klöckener, T.; Hess, S.; Belgardt, B. F.; Paeger, L.; Verhagen, L. A. W.; Husch, A.; Sohn, J.-W.; Hampel, B.; Dhillon, H.; Zigman, J. M. et al.; Lowell, B. B.; Williams, K. W.; Elmquist, J. K.; Horvath, T. L.; Kloppenburg, P.; Brüning, J. C.: High-fat feeding promotes obesity via insulin receptor/PI3k-dependent inhibition of SF-1 VMH neurons. Nature Neuroscience 14 (7), pp. 911 - 918 (2011)

Könner, A. C.; Hess, S.; Tovar, S.; Mesaros, A.; Sanchez-Lasheras, C.; Evers, N.; Verhagen, L. A. W.; Brönneke, H. S.; Kleinridders, A.; Hampel, B. et al.; Kloppenburg, P.; Brüning, J. C.: Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis. Cell Metabolism 13 (6), pp. 720 - 728 (2011)

Li, P.; Cavallero, S.; Gu, Y.; Hughes, J.; Hassan, A. B.; Brüning, J. C.; Pashmforoush, M.; Sucov, H. M.: IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development 138 (9), pp. 1795 - 1805 (2011)

Schubert, M.; Gautam, D.; Surjo, D.; Ueki, K.; Baudler, S.; Schubert, D.; Kondo, T.; Alber, J.; Galldiks, N.; Küstermann, E. et al.; Arndt, S.; Jacobs, A. H.; Krone, W.; Kahn, C. R.; Brüning, J. C.: Role for neuronal insulin resistance in neurodegenerative diseases. Proceedings of the National Academy of Sciences of the United States of America 101 (9), pp. 3100 - 3105 (2004)