Publications of Jan Mauer

Koch, C.E.; Begemann, K.; Kiehn, J.T.; Griewahn, L.; Mauer, J.; Heß, M. E.; Moser, A.; Schmid, S.M.; Brüning, J. C.; Oster, H.: Circadian regulation of hedonic appetite in mice by clocks in dopaminergic neurons of the VTA. Nature Communications 11 (1), 3071 (2020)

Babaei, R.; Schuster, M.; Meln, I.; Lerch, S.; Ghandour, R. A.; Pisani, D. F.; Bayindir-Buchhalter, I.; Marx, J.; Wu, S.; Schoiswohl, G. et al.; Billeter, A. T.; Krunic, D.; Mauer, J.; Lee, Y.-H.; Granneman, J. G.; Fischer, L.; Mueller-Stich, B. P.; Amri, E.-Z.; Kershaw, E. E.; Heikenwaelder, M.; Herzig, S.; Vegiopoulos, A.: Jak-TGF beta cross-talk links transient adipose tissue inflammation to beige adipogenesis. Science Signaling 11 (527), eaai7838 (2018)

Wunderlich, C. M.; Ackermann, J. P.; Ostermann, A. L.; Adams-Quack, P.; Vogt, M. C.; Tran, M.-L.; Nikolajev, A.; Waisman, A.; Garbers, C.; Theurich, S. et al.; Mauer, J.; Hövelmeyer, N.; Wunderlich, F. T.: Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nature Communications 9 (1), 1646 (2018)

Braune, J.; Weyer, U.; Hobusch, C.; Mauer, J.; Brüning, J. C.; Bechmann, I.; Gericke, M.: IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophages in obesity. The Journal of Immunology 198 (7), pp. 2927 - 2934 (2017)

Diaconescu, A. O.; Mathys, C.; Weber, L. A.E.; Kasper, L.; Mauer, J.; Stephan, K. E.: Hierarchical prediction errors in midbrain and septum during social learning. Social Cognitive and Affective Neuroscience 12 (4), pp. 618 - 634 (2017)

Theurich, S.; Tsaousidou, E.; Hanssen, R.; Lempradl, A. M.; Mauer, J.; Timper, K.; Schilbach, K.; Folz-Donahue, K.; Heilinger, C.; Sexl, V. et al.; Pospisilik, J. A.; Wunderlich, F. T.; Brüning, J. C.: IL-6/Stat3-dependent induction of a distinct, obesity-associated NK cell subpopulation deteriorates energy and glucose homeostasis. Cell Metabolism 26 (1), pp. 171 - 184 (2017)

Jais, A.; Solas, M.; Backes, H.; Chaurasia, B.; Kleinridders, A.; Theurich, S.; Mauer, J.; Steculorum, S. M.; Hampel, B.; Goldau, J. et al.; Alber, J.; Förster, C. Y.; Eming, S. A.; Schwaninger, M.; Ferrara, N.; Karsenty, G.; Brüning, J. C.: Myeloid-cell-derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity. Cell 165 (4), pp. 882 - 895 (2016)

Kühn, A. B.; Feis, D.-L.; Schilbach, L.; Kracht, L. W.; Heß, M. E.; Mauer, J.; Brüning, J. C.; Tittgemeyer, M.: FTO gene variant modulates the neural correlates of visual food perception. NeuroImage 128, pp. 21 - 31 (2016)

Oliverio, M.; Schmidt, E.; Mauer, J.; Baitzel, C.; Hansmeier, N.; Khani, S.; Konieczka, S.; Pradas-Juni, M.; Brodesser, S.; Van, T.-M. et al.; Bartsch, D.; Brönneke, H. S.; Heine, M.; Hilpert, H.; Tarcitano, E.; Garinis, G. A.; Frommolt, P.; Heeren, J.; Mori, M. A.; Brüning, J. C.; Kornfeld, J.-W.: Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function. Nature Cell Biology 18 (3), pp. 328 - 336 (2016)

Schmitz, J.; Evers, N.; Awazawa, M.; Nicholls, H. T.; Brönneke, H. S.; Dietrich, A.; Mauer, J.; Blüher, M.; Brüning, J. C.: Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss. Molecular Metabolism 5 (5), pp. 328 - 339 (2016)

Steculorum, S. M.; Ruud, J.; Karakasilioti, I.; Backes, H.; Engström Ruud, L.; Timper, K.; Heß, M. E.; Tsaousidou, E.; Mauer, J.; Vogt, M. C. et al.; Paeger, L.; Bremser, S.; Klein, A. C.; Morgan, D. A.; Frommolt, P.; Brinkkötter, P. T.; Hammerschmidt, P.; Benzing, T.; Rahmouni, K.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue. Cell 165 (1), pp. 125 - 138 (2016)

Mauer, J.; Denson, J. L.; Brüning, J. C.: Versatile functions for IL-6 in metabolism and cancer. Trends in Immunology 36 (2), pp. 92 - 101 (2015)

Sevgi, M.; Rigoux, L.; Kühn, A. B.; Mauer, J.; Schilbach, L.; Heß, M. E.; Gründler, T. O. J.; Ullsperger, M.; Stephan, K. E.; Brüning, J. C. et al.; Tittgemeyer, M.: An obesity-predisposing variant of the FTO gene regulates D2R-dependent reward learning. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 35 (36), pp. 12584 - 12592 (2015)

Kukat, A.; Dogan, S. A.; Edgar, D.; Mourier, A.; Jacoby, C.; Maiti, P.; Mauer, J.; Becker, C.; Senft, K.; Wibom, R. et al.; Kudin, A. P.; Hultenby, K.; Flögel, U.; Rosenkranz, S.; Ricquier, D.; Kunz, W. S.; Trifunovic, A.: Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. PLoS Genetics 10 (6), e1004385 (2014)

Mauer, J.; Chaurasia, B.; Goldau, J.; Vogt, M. C.; Ruud, J.; Nguyen, K. D.; Theurich, S.; Hausen, A. C.; Schmitz, J.; Brönneke, H. S. et al.; Estevez, E.; Allen, T. L.; Mesaros, A.; Partridge, L.; Febbraio, M. A.; Chawla, A.; Wunderlich, F. T.; Brüning, J. C.: Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nature Immunology 15 (5), pp. 423 - 430 (2014)

Turpin, S. M.; Nicholls, H. T.; Willmes, D. M.; Mourier, A.; Brodesser, S.; Wunderlich, C. M.; Mauer, J.; Xu, E.; Hammerschmidt, P.; Brönneke, H. S. et al.; Trifunovic, A.; LoSasso, G.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Krönke, M.; Brüning, J. C.: Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metabolism 20 (4), pp. 678 - 686 (2014)

Vogt, M. C.; Paeger, L.; Hess, S.; Steculorum, S. M.; Awazawa, M.; Hampel, B.; Neupert, S.; Nicholls, H. T.; Mauer, J.; Hausen, A. C. et al.; Predel, R.; Kloppenburg, P.; Horvath, T. L.; Brüning, J. C.: Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding. Cell 156 (3), pp. 495 - 509 (2014)

Gruber, S.; Straub, B.; Ackermann, P. J.; Wunderlich, C. M.; Mauer, J.; Seeger, J. M.; Büning, H.; Heukamp, L.; Kashkar, H.; Schirmacher, P. et al.; Brüning, J. C.; Wunderlich, F. T.: Obesity promotes liver carcinogenesis via Mcl-1 stabilization independent of IL-6Rα signaling. Cell Reports 4 (4), pp. 669 - 680 (2013)

Hult, S.; Soylu, R.; Björklund, T.; Belgardt, B. F.; Mauer, J.; Brüning, J. C.; Kirik, D.; Petersen, A.: Mutant Huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits. Cell Metabolism 13 (4), pp. 428 - 439 (2011)