Publications of Jens Claus Brüning

Journal Article (148)

2015
Journal Article
Knuever, J.; Willenborg, S.; Ding, X.; Akyuez, M. D.; Partridge, L.; Niessen, C. M.; Brüning, J. C.; Eming, S.: Myeloid cell-restricted insulin/IGF-1 receptor deficiency protects against skin inflammation. Journal of Immunology 195 (11), pp. 5296 - 5308 (2015)
Journal Article
Mauer, J.; Denson, J. L.; Brüning, J. C.: Versatile functions for IL-6 in metabolism and cancer. Trends in Immunology 36 (2), pp. 92 - 101 (2015)
Journal Article
Oster, H.; Brüning, J. C.; Lehnert, H.: Transregionaler Sonderforschungsbereich 134: "Ingestive Behaviour: Homeostasis & Reward". Neuroforum 21 (2), pp. 74 - 77 (2015)
Journal Article
Peters, F.; Vorhagen, S.; Brodesser, S.; Jakobshagen, K.; Brüning, J. C.; Niessen, C. M.; Krönke, M.: Ceramide synthase 4 regulates stem cell homeostasis and hair follicle cycling. Journal of Investigative Dermatology 135 (6), pp. 1501 - 1509 (2015)
Journal Article
Ruud, J.; Brüning, J. C.: Metabolism: Light on leptin link to lipolysis. Nature 527 (7576), pp. 43 - 44 (2015)
Journal Article
Sevgi, M.; Rigoux, L.; Kühn, A. B.; Mauer, J.; Schilbach, L.; Heß, M. E.; Gründler, T. O. J.; Ullsperger, M.; Stephan, K. E.; Brüning, J. C. et al.; Tittgemeyer, M.: An obesity-predisposing variant of the FTO gene regulates D2R-dependent reward learning. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 35 (36), pp. 12584 - 12592 (2015)
Journal Article
Steculorum, S. M.; Paeger, L.; Bremser, S.; Evers, N.; Hinze, Y.; Idzko, M.; Kloppenburg, P.; Brüning, J. C.: Hypothalamic UDP increases in obesity and promotes feeding via P2Y6-dependent activation of AgRP neurons. Cell 162 (6), pp. 1404 - 1417 (2015)
Journal Article
Wensveen, F. M.; Jelencic, V.; Valentic, S.; Sestan, M.; Wensveen, T. T.; Theurich, S.; Glasner, A.; Mendrila, D.; Stimac, D.; Wunderlich, F. T. et al.; Brüning, J. C.; Mandelboim, O.; Polic, B.: NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nature Immunology 16 (4), pp. 376 - 385 (2015)
2014
Journal Article
Hess, M. E.; Brüning, J. C.: Obesity: The need to eat-overruling the homeostatic control of feeding. Nature Reviews Endocrinology 10 (1), pp. 5 - 6 (2014)
Journal Article
Hess, M. E.; Brüning, J. C.: The fat mass and obesity-associated (FTO) gene: Obesity and beyond? Biochimica et Biophysica Acta - Molecular Basis of Disease 1842, pp. 2039 - 2047 (2014)
Journal Article
Kornfeld, J.-W.; Brüning, J. C.: Regulation of metabolism by long, non-coding RNAs. Frontiers in Genetics 5, 57 (2014)
Journal Article
Mauer, J.; Chaurasia, B.; Goldau, J.; Vogt, M. C.; Ruud, J.; Nguyen, K. D.; Theurich, S.; Hausen, A. C.; Schmitz, J.; Brönneke, H. S. et al.; Estevez, E.; Allen, T. L.; Mesaros, A.; Partridge, L.; Febbraio, M. A.; Chawla, A.; Wunderlich, F. T.; Brüning, J. C.: Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nature Immunology 15 (5), pp. 423 - 430 (2014)
Journal Article
Nish, S. A.; Schenten, D.; Wunderlich, F. T.; Pope, S. D.; Gao, Y.; Hoshi, N.; Yu, S.; Yan, X.; Lee, H. K.; Pasman, L. et al.; Brodsky, I.; Yordy, B.; Zhao, H.; Brüning, J. C.; Medzhitov, R.: T cell-intrinsic role of IL-6 signaling in primary and memory responses. eLife (3), 01949 (2014)
Journal Article
Patti, G. J.; Tautenhahn, R.; Johannsen, D.; Kalisiak, E.; Ravussin, E.; Brüning, J. C.; Dillin, A.; Siuzdak, G.: Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension. Metabolomics 10 (4), pp. 737 - 743 (2014)
Journal Article
Schenten, D.; Nish, S. A.; Yu, S.; Yan, X.; Lee, H. K.; Brodsky, I.; Pasman, L.; Yordy, B.; Wunderlich, F. T.; Brüning, J. C. et al.; Zhao, H.; Medzhitov, R.: Signaling through the adaptor molecule MyD88 in CD4(+) T cells is required to overcome suppression by regulatory T cells. Immunity 40 (1), pp. 78 - 90 (2014)
Journal Article
Steculorum, S. M.; Brüning, J. C.: Die another day: A painless path to longevity. Cell 157 (5), pp. 1004 - 1006 (2014)
Journal Article
Steculorum, S. M.; Solas, M.; Brüning, J. C.: The paradox of neuronal insulin action and resistance in the development of aging-associated diseases. Alzheimer's and Dementia 10 (1, Suppl.), pp. S3 - S11 (2014)
Journal Article
Tsaousidou, E.; Paeger, L.; Belgardt, B. F.; Pal, M.; Wunderlich, C. M.; Brönneke, H. S.; Collienne, U.; Hampel, B.; Wunderlich, F. T.; Schmidt-Supprian, M. et al.; Kloppenburg, P.; Brüning, J. C.: Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance. Cell Reports 9 (4), pp. 1495 - 1506 (2014)
Journal Article
Turpin, S. M.; Nicholls, H. T.; Willmes, D. M.; Mourier, A.; Brodesser, S.; Wunderlich, C. M.; Mauer, J.; Xu, E.; Hammerschmidt, P.; Brönneke, H. S. et al.; Trifunovic, A.; LoSasso, G.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Krönke, M.; Brüning, J. C.: Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metabolism 20 (4), pp. 678 - 686 (2014)
Journal Article
Vogt, M. C.; Paeger, L.; Hess, S.; Steculorum, S. M.; Awazawa, M.; Hampel, B.; Neupert, S.; Nicholls, H. T.; Mauer, J.; Hausen, A. C. et al.; Predel, R.; Kloppenburg, P.; Horvath, T. L.; Brüning, J. C.: Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding. Cell 156 (3), pp. 495 - 509 (2014)
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