Publications of Frank Thomas Wunderlich
All genres
Journal Article (68)
21.
Journal Article
50 (5), pp. 1232 - 1248.e14 (2019)
Enzymatic activity of HPGD in Treg cells suppresses Tconv cells to maintain adipose tissue homeostasis and prevent metabolic dysfunction. Immunity 22.
Journal Article
50, 75 (2018)
Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus. Experimental and Molecular Medicine 23.
Journal Article
32 (1), pp. 72 - 82 (2018)
Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-kappa B signaling. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 24.
Journal Article
17, pp. 122 - 133 (2018)
Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma. Molecular Metabolism 25.
Journal Article
9 (1), 1646 (2018)
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nature Communications 26.
Journal Article
23 (12), pp. 1466 - 1473 (2017)
A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nature Medicine 27.
Journal Article
65 (1), pp. 89 - 103 (2017)
IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice. Hepatology 28.
Journal Article
198 (7), pp. 2747 - 2759 (2017)
Roquin paralogs differentially regulate functional NKT cell subsets. Journal of Immunology 29.
Journal Article
18 (1), pp. 74 - 85 (2017)
Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T H 17 cells. Nature Immunology 30.
Journal Article
8 (1), 153 (2017)
Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nature Communications 31.
Journal Article
91 (6), pp. 1510 - 1517 (2017)
Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes. Kidney International: Official Journal of the International Society of Nephrology 32.
Journal Article
469 (3-4), pp. 385 - 396 (2017)
Macrophage function in obesity-induced inflammation and insulin resistance. Pflügers Archiv: European Journal of Physiology 33.
Journal Article
8, 15069 (2017)
Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis. Nature Communications 34.
Journal Article
26 (1), pp. 171 - 184 (2017)
IL-6/Stat3-dependent induction of a distinct, obesity-associated NK cell subpopulation deteriorates energy and glucose homeostasis. Cell Metabolism 35.
Journal Article
19 (2), pp. 267 - 280 (2017)
IL-6 improves energy and glucose homeostasis in obesity via enhanced central IL-6 trans-signaling. Cell Reports 36.
Journal Article
66 (2), pp. 616 - 630 (2017)
The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. Hepatology 37.
Journal Article
8, 14803 (2017)
Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance. Nature Communications 38.
Journal Article
11 (3), e0151913 (2016)
IL-6 signaling in myelomonocytic cells is not crucial for the development of IMQ-induced psoriasis. PLoS One 39.
Journal Article
127 (22), pp. 2732 - 2741 (2016)
B-cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B-cell lymphoma in mice. Blood 40.
Journal Article
6, 35400 (2016)
Single and transient Ca2+ peaks in podocytes do not induce changes in glomerular filtration and perfusion. Scientific Reports