Publications of Frank Thomas Wunderlich

Journal Article (76)

2014
Journal Article
Sommer, D.; Peters, A.; Wirtz, T.; Mai, M.; Ackermann, J.; Thabet, J.; Schmidt, J.; Weighardt, H.; Wunderlich, F. T.; Degen, J. et al.; Schultze, J. L.; Beyer, M.: Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nature Communications 5, 3045 (2014)
Journal Article
Tsaousidou, E.; Paeger, L.; Belgardt, B. F.; Pal, M.; Wunderlich, C. M.; Brönneke, H. S.; Collienne, U.; Hampel, B.; Wunderlich, F. T.; Schmidt-Supprian, M. et al.; Kloppenburg, P.; Brüning, J. C.: Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance. Cell Reports 9 (4), pp. 1495 - 1506 (2014)
Journal Article
Turpin, S. M.; Nicholls, H. T.; Willmes, D. M.; Mourier, A.; Brodesser, S.; Wunderlich, C. M.; Mauer, J.; Xu, E.; Hammerschmidt, P.; Brönneke, H. S. et al.; Trifunovic, A.; LoSasso, G.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Krönke, M.; Brüning, J. C.: Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metabolism 20 (4), pp. 678 - 686 (2014)
2013
Journal Article
Ackermann, B.; Kröber, S.; Torres-Benito, L.; Borgmann, A.; Peters, M.; Barkooie, S. M. H.; Tejero, R.; Jakubik, M.; Schreml, J.; Mibradt, J. et al.; Wunderlich, F. T.; Riessland, M.; Tabares, L.; Wirth, B.: Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality. Human Molecular Genetics 22 (7), pp. 1328 - 1347 (2013)
Journal Article
Gruber, S.; Straub, B.; Ackermann, P. J.; Wunderlich, C. M.; Mauer, J.; Seeger, J. M.; Büning, H.; Heukamp, L.; Kashkar, H.; Schirmacher, P. et al.; Brüning, J. C.; Wunderlich, F. T.: Obesity promotes liver carcinogenesis via Mcl-1 stabilization independent of IL-6Rα signaling. Cell Reports 4 (4), pp. 669 - 680 (2013)
Journal Article
Pal, M.; Wunderlich, C. M.; Spohn, G.; Broenneke, H. S.; Schmidt-Supprian, M.; Wunderlich, F. T.: Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice. PLoS ONE 8 (1), e54247 (2013)
Journal Article
Peche, V. S.; Holak, T. A.; Burgute, B. D.; Kosmas, K.; Kale, S. P.; Wunderlich, F. T.; Elhamine, F.; Stehle, R.; Pfitzer, G.; Nohroudi, K. et al.; Addicks, K.; Stöckigt, F.; Schrickel, J. W.; Gallinger, J.; Schleicher, M.; Noegel, A. A.: Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy. Cellular and Molecular Liefe Sciences 70 (3), pp. 527 - 543 (2013)
Journal Article
Ruud, J.; Wilhelms, D. B.; Nilsson, A.; Eskilsson, A.; Tang, Y.-J.; Ströhle, P.; Caesar, R.; Schwaninger, M.; Wunderlich, F. T.; Bäckhed, F. et al.; Engblom, D.; Blomqvist, A.: Inflammation-and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells. FASEB Journal 27 (5), pp. 1973 - 1980 (2013)
Journal Article
Stöhr, O.; Schilbach, K.; Moll, L.; Hettich, M. M.; Freude, S.; Wunderlich, F. T.; Ernst, M.; Zemva, J.; Brüning, J. C.; Krone, W. et al.; Udelhoven, M.; Schubert, M.: Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. AGE 35 (1), pp. 83 - 101 (2013)
Journal Article
Tovar, S.; Paeger, L.; Hess, S.; Morgan, D. A.; Hausen, A. C.; Brönneke, H. S.; Hampel, B.; Ackermann, P. J.; Evers, N.; Büning, H. et al.; Wunderlich, F. T.; Rahmouni, K.; Kloppenburg, P.; Brüning, J. C.: KATP-Channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis. Cell Metabolism 18 (3), pp. 445 - 455 (2013)
Journal Article
Yasuda, T.; Wirtz, T.; Zhang, B.; Wunderlich, F. T.; Schmid-Supprian, M.; Sommermann, T.; Rajewsky, K.: Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice. Cold Spring Harbor Symposia on Quantitative Biology 78 (1), pp. 259 - 263 (2013)
2012
Journal Article
Whitham, M.; Chan, M. H. S.; Pal, M.; Matthews, V. B.; Prelovsek, O.; Lunke, S.; El-Osta, A.; Brönneke, H.; Alber, J.; Brüning, J. C. et al.; Wunderlich, F. T.; Lancaster, G. I.; Febbraio, M. A.: Contraction-induced IL-6 gene transcription in skeletal muscle is regulated by c-jun terminal kinase/Activator protein-1. Journal of Biological Chemistry 287 (14), pp. 10771 - 10779 (2012)
Journal Article
Wunderlich, C. M.; Delic, D.; Behnke, K.; Meryk, A.; Stroehle, P.; Chaurasia, B.; Al-Quraishy, S.; Wunderlich, F.; Brüning, J. C.; Wunderlich, F. T.: Cutting edge: inhibition of IL-6 trans-signaling protects from Malaria-induced lethality in mice. Journal of Immunology 188 (9), pp. 4141 - 4144 (2012)
2011
Journal Article
Bertossi, A.; Aichinger, M.; Sansonetti, P.; Lech, M.; Neff, F.; Pal, M.; Wunderlich, F. T.; Anders, H.-J.; Klein, L.; Schmidt-Supprian, M.: Loss of Roquin induces early death and immune deregulation but not autoimmunity. Journal of Experimental Medicine 208 (9), pp. 1749 - 1756 (2011)
Journal Article
Chaudhry, A.; Samstein, R. M.; Treuting, P.; Liang, Y.; Pils, M. C.; Heinrich, J.-M.; Jack, R. S.; Wunderlich, F. T.; Brüning, J. C.; Müller, W. et al.; Rudensky, A. Y.: Interleukin-10 signaling in regulatory T cells Is required for suppression of Th17 cell-mediated inflammation. Immunity 34 (4), pp. 566 - 578 (2011)
Journal Article
Jordan, S. D.; Krüger, M.; Willmes, D. M.; Redemann, N.; Wunderlich, F. T.; Brönneke, H. S.; Merkwirth, C.; Kashkar, H.; Olkkonen, V. M.; Böttger, T. et al.; Braun, T.; Seibler, J.; Brüning, J. C.: Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nature Cell Biology 13 (4), pp. 434 - 446 (2011)
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