Publications of Frank Thomas Wunderlich

von Loeffelholz, C.; Lieske, S.; Neuschäfer-Rube, F.; Willmes, D. M.; Raschzok, N.; Sauer, I. M.; König, J.; Fromm, M. F.; Horn, P.; Chatzigeorgiou, A. et al.; Pathe-Neuschäfer-Rube, A.; Jordan, J.; Pfeiffer, A. F.H.; Mingrone, G.; Bornstein, S. R.; Ströhle, P.; Harms, C.; Wunderlich, F. T.; Helfand, S. L.; Bernier, M.; de Cabo, R.; Shulman, G. I.; Chavakis, T.; Püschel, G. P.; Birkenfeld, A. L.: The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. Hepatology 66 (2), pp. 616 - 630 (2017)

Xu, E.; Pereira, M. M.; Karakasilioti, I.; Theurich, S.; Al-Maari, M.; Rappl, G.; Waisman, A.; Wunderlich, F. T.; Brüning, J. C.: Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance. Nature Communications 8, 14803 (2017)

Klebow, S.; Hahn, M.; Nikoalev, A.; Wunderlich, F. T.; Hövelmeyer, N.; Karbach, S. H.; Waisman, A.: IL-6 signaling in myelomonocytic cells is not crucial for the development of IMQ-induced psoriasis. PLoS One 11 (3), e0151913 (2016)

Knittel, G.; Liedgens, P.; Korovkina, D.; Seeger, J. M.; Al-Baldawi, Y.; Al-Maarri, M.; Fritz, C.; Vlantis, K.; Bezhanova, S.; Scheel, A. H. et al.; Wolf, O.-O.; Reimann, M.; Möller, P.; Lopez, C.; Schlesner, M.; Lohneis, P.; Weber, A. N.R.; Trümper, L.; Staudt, L. M.; Ortmann, M.; Pasparakis, M.; Siebert, R.; Schmitt, C. A.; Klatt, A. R.; Wunderlich, F. T.; Schäfer, S. C.; Persigehl, T.; Montesinos-Rongen, M.; Odenthal, M.; Büttner, R.; Frenzel, L. P.; Kashkar, H.; Reinhard, H. C.: B-cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B-cell lymphoma in mice. Blood 127 (22), pp. 2732 - 2741 (2016)

Koehler, S.; Brähler, S.; Kuczkowski, A.; Binz, J.; Hackl, M. J.; Hagmann, H.; Höhne, M.; Vogt, M. C.; Wunderlich, C. M.; Wunderlich, F. T. et al.; Schweda, F.; Schermer, B.; Benzing, T.; Brinkkoetter, P. T.: Single and transient Ca2+ peaks in podocytes do not induce changes in glomerular filtration and perfusion. Scientific Reports 6, 35400 (2016)

Nguyen, P.-H.; Fedorchenko, O.; Rosen, N.; Koch, M.; Barthel, R.; Winarski, T.; Florin, A.; Wunderlich, F. T.; Reinart, N.; Hallek, M.: LYN kinase in the tumor microenvironment is essential for the progression of chronic lymphocytic leukemia. Cancer Cell 30 (4), pp. 610 - 622 (2016)

Steculorum, S. M.; Ruud, J.; Karakasilioti, I.; Backes, H.; Engström Ruud, L.; Timper, K.; Heß, M. E.; Tsaousidou, E.; Mauer, J.; Vogt, M. C. et al.; Paeger, L.; Bremser, S.; Klein, A. C.; Morgan, D. A.; Frommolt, P.; Brinkkötter, P. T.; Hammerschmidt, P.; Benzing, T.; Rahmouni, K.; Wunderlich, F. T.; Kloppenburg, P.; Brüning, J. C.: AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue. Cell 165 (1), pp. 125 - 138 (2016)

Baris, O. R.; Ederer, S.; Neuhaus , J. F. G.; von Kleist-Retzow, J.-C.; Wunderlich, C.; Pal, M.; Wunderlich, F. T.; Peeva, V.; Zsurka, G.; Kunz , W. S. et al.; Hickethier, T.; Bunck, A. C.; Stöckigt, F.; Schrickel, J. W.; Wiesner , R. J.: Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging. Cell Metabolism 21 (6), pp. 667 - 677 (2015)

Bultmann-Mellin, I.; Conradi, A.; Maul, A. C.; Dinger, K.; Wempe, F.; Wohl, A. P.; Imhof, T.; Wunderlich, F. T.; Bunck, A. C.; Nakamura, T. et al.; Bloch, W.; Ghanem, A.; Heinz, A.; Von Melchner, H.; Sengle, G.; Sterner-Kock, A.: Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms. Disease Models and Mechanisms 8 (4), pp. 403 - 415 (2015)

Rastetter, R. H.; Blömacher, M.; Drebber, U.; Marko, M.; Behrens, J.; Soiga, R.; Hojeili, S.; Bhattacharya, K.; Wunderlich, C. M.; Wunderlich, F. T. et al.; Odenthal, M.; Ziemann, A.; Eichinger, L.; Clemen, C. S.: Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling. BMC Cancer 15 (1), 638 (2015)

Wensveen, F. M.; Jelencic, V.; Valentic, S.; Sestan, M.; Wensveen, T. T.; Theurich, S.; Glasner, A.; Mendrila, D.; Stimac, D.; Wunderlich, F. T. et al.; Brüning, J. C.; Mandelboim, O.; Polic, B.: NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nature Immunology 16 (4), pp. 376 - 385 (2015)

Andree, M.; Seeger, J. M.; Schüll, S.; Coutelle, O.; Wagner-Stippich, D.; Wiegmann, K.; Wunderlich, C. M.; Brinkmann, K.; Broxtermann, P.; Witt, A. et al.; Fritsch, M.; Martinelli, P.; Bielig, H.; Lamkemeyer, T.; Rugarli, E. I.; Kaufmann, T.; Sterner-Kock, A.; Wunderlich, F. T.; Villunger, A.; Martins, L. M.; Krönke, M.; Kufer, T. A.; Utermöhlen, O.; Kashkar, H.: BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO Journal 33 (19), pp. 2171 - 2187 (2014)

Geibel, M.; Badurek, S.; Horn, J. M.; Vatanashevanopakorn, C.; Koudelka, J.; Wunderlich, C. M.; Brönneke, H. S.; Wunderlich, F. T.; Minichiello, L.: Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity. Nature Communications 5, 3427 (2014)

Lepperhof, V.; Polchynski, O.; Kruttwig, K.; Brüggemann, C.; Neef, K.; Drey, F.; Zheng, Y.; Ackermann, J. P.; Choi, Y.-H.; Wunderlich, F. T. et al.; Höhn, M.; Hescheler, J.; Saric, T.: Bioluminescent imaging of genetically selected induced pluripotent stem cell-derived cardiomyocytes after transplantation into infarcted heart of syngeneic recipients. PLoS ONE 9 (9), e107363 (2014)

Mauer, J.; Chaurasia, B.; Goldau, J.; Vogt, M. C.; Ruud, J.; Nguyen, K. D.; Theurich, S.; Hausen, A. C.; Schmitz, J.; Brönneke, H. S. et al.; Estevez, E.; Allen, T. L.; Mesaros, A.; Partridge, L.; Febbraio, M. A.; Chawla, A.; Wunderlich, F. T.; Brüning, J. C.: Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nature Immunology 15 (5), pp. 423 - 430 (2014)

Nish, S. A.; Schenten, D.; Wunderlich, F. T.; Pope, S. D.; Gao, Y.; Hoshi, N.; Yu, S.; Yan, X.; Lee, H. K.; Pasman, L. et al.; Brodsky, I.; Yordy, B.; Zhao, H.; Brüning, J. C.; Medzhitov, R.: T cell-intrinsic role of IL-6 signaling in primary and memory responses. eLife (3), 01949 (2014)

Schenten, D.; Nish, S. A.; Yu, S.; Yan, X.; Lee, H. K.; Brodsky, I.; Pasman, L.; Yordy, B.; Wunderlich, F. T.; Brüning, J. C. et al.; Zhao, H.; Medzhitov, R.: Signaling through the adaptor molecule MyD88 in CD4(+) T cells is required to overcome suppression by regulatory T cells. Immunity 40 (1), pp. 78 - 90 (2014)

Sommer, D.; Peters, A.; Wirtz, T.; Mai, M.; Ackermann, J.; Thabet, J.; Schmidt, J.; Weighardt, H.; Wunderlich, F. T.; Degen, J. et al.; Schultze, J. L.; Beyer, M.: Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nature Communications 5, 3045 (2014)

Tsaousidou, E.; Paeger, L.; Belgardt, B. F.; Pal, M.; Wunderlich, C. M.; Brönneke, H. S.; Collienne, U.; Hampel, B.; Wunderlich, F. T.; Schmidt-Supprian, M. et al.; Kloppenburg, P.; Brüning, J. C.: Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance. Cell Reports 9 (4), pp. 1495 - 1506 (2014)

Turpin, S. M.; Nicholls, H. T.; Willmes, D. M.; Mourier, A.; Brodesser, S.; Wunderlich, C. M.; Mauer, J.; Xu, E.; Hammerschmidt, P.; Brönneke, H. S. et al.; Trifunovic, A.; LoSasso, G.; Wunderlich, F. T.; Kornfeld, J.-W.; Blüher, M.; Krönke, M.; Brüning, J. C.: Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metabolism 20 (4), pp. 678 - 686 (2014)