Talk by Anne Schaefer, MD, PhD

Epigenetic control of neurodegeneration

  • Date: Jun 3, 2016
  • Time: 02:00 PM c.t. - 03:00 PM (Local Time Germany)
  • Speaker: Anne Schaefer, MD, PhD
  • Assistant Professor, Seaver Fellow, Friedman Brain Institute, Department of Neuroscience, Department of Psychiatry Icahn School of Medicine at Mount Sinai, New York, USA
  • Location: MPI for Metabolism Research, Gleueler Strasse 50, 50931 Köln
  • Room: Seminar room 1
  • Host: Prof. Jens Brüning
  • Contact:
Talk by Anne Schaefer, MD, PhD
"Neurodegeneration is one of the major causes of age-related cognitive decline. While the etiology of neurodegenerative processes may differ from being genetically predetermined to environmentally induced, the common path of the disease frequently involves the loss of neuronal-cell type specific identity. We have identified epigenetic mechanisms that are critical for the maintenance of neuron identity in the adult brain. In my presentation, I will focus on the epigenetic control of feed-forward transcriptional networks that, once activated, can drive progressive age-related neurodegeneration. I will also discuss the significance of our findings in the context of neurodegenerative diseases such as Huntington’s disease and Spinocerebellar Ataxia."
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