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August 2015
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The Max Planck Institute for Metabolism Research

Maintenance of energy homeostasis, i.e. the balance between caloric intake and energy expenditure, has to be maintained in a tight range to ensure metabolic homeostasis, health, and survival of any organism.

Throughout evolution, a sophisticated neuronal network has developed that integrates information from the periphery of the organism about the energy availability of the body. This network enables the body to adapt a wide range of behavioral and autonomic responses to precisely control food intake, energy expenditure, and substrate flux across different peripheral organs. [more]
 
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