Prof. Dr. Rudolf Graf

Curriculum vitae - Rudolf Graf

Education and Professional Experience

  • 1974
    University degree in biology, Ruhr University, Bochum, Germany
  • 1978
    Dissertation with Werner Rautenberg, Institute of Animal Physiology, Ruhr University, Bochum, Germany
  • 1978-1980
    Postdoc, Institute of Animal Physiology, Ruhr University, Bochum, Germany
  • 1980-1982
    Postdoc, lab of Craig Heller, Department of Biology, Stanford University, CA, USA
  • 1983-2005
    Research Associate, Departement of Neurology, Director Wolf-Dieter Heiss, Max Planck Institute for Neurological Research, Cologne, Germany
  • 1992
    Habilitation (Experimental Neurology), Medical Faculty, University of Cologne, Cologne, Germany
  • since 1998
    Adjunct Professor, Medical Faculty, University of Cologne, Cologne, Germany
  • 2005-2014
    Deputy Managing Director and Research Group Leader for Multimodal Imaging of Brain Metabolism, Max Planck Institute for Neurological Research, Cologne, Germany
  • Since 2014
    Research Group Leader for Multimodal Imaging of Brain Metabolism, Max Planck Institute for Metabolism Research, (formerly Max Planck Institute for Neurological Research), Cologne, Germany

Professional Memberships and Activities

  • Board of Directors German Competence Network Stroke
  • German Neurological Society
  • German Stroke Society
  • German Zoological Society
  • International Society for Cerebral Blood Flow & Metabolism
  • Society for Neuroscience
  • Steering Committee of the COSBID Study Group

Key Scientific Expertise

Experimental Neurology / Experimental Stroke / Cortical Spreading Depolarization

Positron Emission Tomography / Real-Time Optical Imaging / Electrophysiology / Microdialysis

Selected Publications

  1. Strong AJ, Anderson PJ, Watts HR, Virley DJ, Lloyd A, Irving EA, Nagafuji T, Ninomiya M, Nakamura H, Dunn AK, Graf R (2007) Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex. Brain 130:995-1008.
  2. Dohmen C, Sakowitz OW, Fabricius M, Bosche B, Reithmeier T, Ernestus RI, Brinker G, Dreier JP, Woitzik J, Strong AJ, Graf R (2008) Spreading depolarizations occur in human ischemic stroke with high incidence. Annals of Neurology 63:720-8.
  3. Bosche B*, Graf R*, Ernestus RI, Dohmen C, Reithmeier T, Brinker G, Strong AJ, Dreier JP, Woitzik J (2010) Recurrent Spreading Depolarizations after Subarachnoid Hemorrhage Decreases Oxygen Availability in Human Cerebral Cortex. Annals of Neurology 67:607-17.
  4. Nakamura H, Strong AJ, Dohmen C, Sakowitz OW, Vollmar S, Sue M, Kracht L, Hashemi P, Bhatia R, Yoshimine T, Dreier JP, Dunn AK, Graf R (2010) Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions. Brain 133:1994­-2006.
  5. Gramer M, Feuerstein D, Steimers A, Takagaki M, Kumagai T, Sue M, Vollmar S, Kohl-Bareis M, Backes H, Graf R (2014) Device for simultaneous positron emission tomography, laser speckle imaging and RGB reflectometry: Validation and application to cortical spreading depression and brain ischemia in rats. Neuroimage 94:250-262.
 
loading content