Publikationen von Jens C. Brüning

Vogt, M. C.; Paeger, L.; Hess, S.; Steculorum, S. M.; Awazawa, M.; Hampel, B.; Neupert, S.; Nicholls, H. T.; Mauer, J.; Hausen, A. C. et al.; Predel, R.; Kloppenburg, P.; Horvath, T. L.; Brüning, J. C.: Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding. Cell 156 (3), S. 495 - 509 (2014)

Gahete, M. D.; Cordoba-Chacon, J.; Lin, Q.; Brüning, J. C.; Kahn, C. R.; Castano, J. P.; Christian, H.; Luque, R. M.; Kineman, R. D.: Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms. Endocrinology 154 (7), S. 2410 - 2420 (2013)

Gruber, S.; Straub, B.; Ackermann, P. J.; Wunderlich, C. M.; Mauer, J.; Seeger, J. M.; Büning, H.; Heukamp, L.; Kashkar, H.; Schirmacher, P. et al.; Brüning, J. C.; Wunderlich, F. T.: Obesity promotes liver carcinogenesis via Mcl-1 stabilization independent of IL-6Rα signaling. Cell Reports 4 (4), S. 669 - 680 (2013)

Günschmann, C.; Stachelscheid, H.; Akyüz, M. D.; Schmitz, A.; Missero, C.; Brüning, J. C.; Niessen, C. M.: Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition. Developmental Cell 26 (2), S. 176 - 187 (2013)

Hess, M. E.; Hess, S.; Meyer, K. D.; Verhagen, L. A. W.; Koch, L.; Brönneke, H. S.; Dietrich, M. O.; Jordan, S. D.; Saletore, Y.; Elemento, O. et al.; Belgardt, B. F.; Franz, T.; Horvath, T. L.; Rüther, U.; Jaffrey, S. R.; Kloppenburg, P.; Brüning, J. C.: The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nature Neuroscience 16 (8), S. 1042 - 1048 (2013)

Karra, E.; O'Daly, O. G.; Choudhury, A. I.; Yousseif, A.; Millership, S.; Neary, M. T.; Scott, W. R.; Chandarana, K.; Manning, S.; Hess, M. E. et al.; Iwakura, H.; Akamizu, T.; Millet, Q.; Gelegen, C.; Drew, M. E.; Rahman, S.; Emmanuel, J. J.; Williams, S. C. R.; Rüther, U. U.; Brüning, J. C.; Withers, D. J.; Zelaya, F. O.; Batterham, R. L.: A link between FTO, ghrelin, and impaired brain food-cue responsivity. Journal of Clinical Investigation 123 (8), S. 3539 - 3551 (2013)

Kornfeld, J.-W.; Baitzel, C.; Könner, C. A.; Nicholls, H. T.; Vogt, M. C.; Hermanns, K.; Scheja, L.; Haumaitre, C.; Wolf, A. M.; Knippschild, U. et al.; Seibler, J.; Cereghini, S.; Heeren, J.; Stoffel, M.; Brüning, J. C.: Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature 494 (7435), S. 111 - 115 (2013)

Newton, A. J.; Hess, S.; Paeger, L.; Vogt, M. C.; Lascano, J. F.; Nillni, E. A.; Brüning, J. C.; Kloppenburg, P.; Xu, A. W.: AgRP innervation onto POMC neurons increases with age and is accelerated with chronic high-fat feeding in male mice. Endocrinology 154 (1), S. 172 - 183 (2013)

Steculorum, S. M.; Vogt, M. C.; Brüning, J. C.: Perinatal programming of metabolic diseases. Role of insulin in the development of hypothalamic neurocircuits. Endocrinology and Metabolism Clinics of North America 42 (1), S. 149 - 164 (2013)

Stöhr, O.; Schilbach, K.; Moll, L.; Hettich, M. M.; Freude, S.; Wunderlich, F. T.; Ernst, M.; Zemva, J.; Brüning, J. C.; Krone, W. et al.; Udelhoven, M.; Schubert, M.: Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. AGE 35 (1), S. 83 - 101 (2013)

Tovar, S.; Paeger, L.; Hess, S.; Morgan, D. A.; Hausen, A. C.; Brönneke, H. S.; Hampel, B.; Ackermann, P. J.; Evers, N.; Büning, H. et al.; Wunderlich, F. T.; Rahmouni, K.; Kloppenburg, P.; Brüning, J. C.: KATP-Channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis. Cell Metabolism 18 (3), S. 445 - 455 (2013)

Vogt, M. C.; Brüning, J. C.: CNS insulin signaling in the control of energy homeostasis and glucose metabolism - from embryo to old age. Trends in Endocrinology and Metabolism 24 (2), S. 76 - 84 (2013)

Aghdam, S. Y.; Eming, S. E.; Willenborg, S.; Neuhaus, B.; Niessen, C. M.; Partridge, L.; Krieg, T.; Brüning, J. C.: Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochemical and Biophysical Research Communications 421 (2), S. 197 - 202 (2012)

Blumbach, K.; Niehoff, A.; Belgardt, B. F.; Ehlen, H. W. A.; Schmitz, M.; Hallinger, R.; Schulz, J.-N.; Brüning, J. C.; Krieg, T.; Schubert, M. et al.; Guilberg, D.; Eckes, B.: Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels. Journal of Biological Chemistry 287 (9), S. 6431 - 6440 (2012)

Könner, A. C.; Brüning, J. C.: Mapping leptin's link to reproduction. Molecular Metabolism 1 (1-2), S. 5 - 7 (2012)

Könner, A. C.; Brüning, J. C.: Selective insulin and leptin resistance in metabolic disorders. Cell Metabolism 16 (2), S. 144 - 152 (2012)

Kornfeld, J.-W.; Brüning, J. C.: MyomiRs-133a/b turn off the heat. Nature Cell Biology 14 (12), S. 1248 - 1249 (2012)

Rother, E.; Belgardt, B. F.; Tsaousidou, E.; Hampel, B.; Waisman, A.; Myers, M. G.; Brüning, J. C.: Acute selective ablation of rat insulin promoter-expressing (RIP HER) neurons defines their orexigenic nature. Proceedings of the National Academy of Sciences of the United States of America 109 (44), S. 18132 - 18137 (2012)

Tschöp, M. H.; Speakman, J. R.; Arch, J. R. S.; Auwerx, J.; Brüning, J. C.; Chan, L.; Eckel, R. H.; Farese, R. V.; Galgani, J. E.; Hambly, C. et al.; Herman, M. A.; Horvath, T. L.; Kahn, B. B.; Kozma, S. C.; Maratos-Flier, E.; Müller, T. D.; Münzberg, H.; Pfluger, P. T.; Plum, L.; Reitman, M. L.; Rahmouni, K.; Shulman, G. I.; Thomas, G.; Kahn, C. R.; Ravussin, E.: A guide to analysis of mouse energy metabolism. Nature Methods 9 (1), S. 57 - 63 (2012)

Whitham, M.; Chan, M. H. S.; Pal, M.; Matthews, V. B.; Prelovsek, O.; Lunke, S.; El-Osta, A.; Brönneke, H.; Alber, J.; Brüning, J. C. et al.; Wunderlich, F. T.; Lancaster, G. I.; Febbraio, M. A.: Contraction-induced IL-6 gene transcription in skeletal muscle is regulated by c-jun terminal kinase/Activator protein-1. Journal of Biological Chemistry 287 (14), S. 10771 - 10779 (2012)