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VERSION:2.0
PRODID:icalendar-ruby
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METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20260609T212329Z
UID:https://www.sf.mpg.de/events/45340/2285
DTSTART:20260414T120000Z
DTEND:20260414T130000Z
CLASS:PUBLIC
CREATED:20260409T152903Z
DESCRIPTION:Overnutrition\, inflammation\, and genetic aberrations promote 
 the accumulation of sphingolipids such as ceramides\, which alter metaboli
 c programs and induce apoptosis in a wide range of cell types.In humans\, 
 serum ceramides are biomarkers of diabetes and major adverse cardiac event
 s\, and clinics have started measuring circulating ceramides as markers of
  disease risk.In rodents\, inhibiting ceramide biosynthesis ameliorates di
 abetes\, steatohepatitis\, kidney injury\, and heart failure. The author w
 ill discuss the evolution of this pathway as a signal of lipid excess and 
 the therapeutic potential of a new approach to inactivate ceramides and co
 mbat cardiometabolic pathologies.\nSpeaker: Scott A. Summers\, PhD
LAST-MODIFIED:20260409T152903Z
LOCATION:MPI for Metabolism Research\, Gleueler Strasse 50\, 50931 Köln\, 
 Room: Seminar room 1
SUMMARY:Destickifying Ceramides to Treat Cardiometabolic Disease:  Talk by 
 Prof. Scott Summers\, Phd\, University of Utah\, Salt Lake City\, USA
URL;VALUE=URI:https://www.sf.mpg.de/events/45340/2285
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